ReviewCureus2022
Opportunities and Significance of Nanoparticle-DNA Binding in Medical Biotechnology: A Review.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Rising adoption of imageless navigation in total hip arthroplasty for morbid obesity: do clinical outcomes improve? A matched cohort study.International orthopaedics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bionanotechnology is a budding area that combines engineering and biomedical sciences through the development of new functional systems and devices, especially related to medical use and their applications. DNA nanotechnology is one of the most widely studied fields for highly selective biosensing, imaging, drug delivery, and diagnostic purposes. Nanotechnology efficiently serves as a bridge between biotechnology and medical technology, and it offers great potential for medical and healthcare improvements. This has aroused a lot of scientific importance in the last few years owing to their exceptional practical capabilities and growing implementations in industrial and healthcare mechanics. Now, various research is being conducted to understand how nanoparticles can alter DNA sequences and their structures. Recent experiments using circular dichroism and fluorescence tests show that nanoparticle binding produces a flexible conformational shift in the structure of DNA. Additionally, the nanoparticle's affinity for the DNA may very well be influenced by external agents, albeit the complex is stable at rather high ionic firmness. This review gives an account of the mechanism of DNA-nanoparticle binding, with the binding of distinct types of nanoparticles and their interactions, how they change the structure of DNA, and their therapeutic uses and talks about their cytotoxic effects on humans and the environment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.