Evidence map›Paper›PMID 36474810›Full record

ReviewOsteoarthritis and cartilage open2021

Evaluation of osteoarthritic features in peripheral joints by ultrasound imaging: A systematic review.

Prue Molyneux, Catherine Bowen, Richard Ellis, Keith Rome, Mike Frecklington, Matthew Carroll

Abstract readReview
In one paragraph

Review in Osteoarthritis and cartilage open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Clinical and Sonographic Pattern of Late-Onset and Early-Onset Rheumatoid Arthritis: Comparative Study.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prue MolyneuxSchool of Clinical Sciences, Auckland University of Technology, New Zealand.
Catherine BowenSchool of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton, UK.
Richard EllisSchool of Clinical Sciences, Auckland University of Technology, New Zealand.
Keith RomeSchool of Clinical Sciences, Auckland University of Technology, New Zealand.
Mike FrecklingtonSchool of Clinical Sciences, Auckland University of Technology, New Zealand.
Matthew CarrollSchool of Clinical Sciences, Auckland University of Technology, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine how structural and inflammatory osteoarthritis (OA) features in peripheral joints are assessed, defined and graded by ultrasound (US) imaging. Design: MEDLINE, CINAHL, Cochrane and SPORTDiscus were systematically searched in March 2021. To be eligible, studies needed to (1) include participants with peripheral joint OA, and (2) used grey scale USI or power Doppler (PD) to assess one or more US features in peripheral joints of the hands and feet. Methodological quality of all included studies was assessed using the Critical Appraisal Skills Program (CASP) tool. Results: A total of 159 citations were identified for screening. Thirty-two articles were included for final analysis and were of good methodological quality. Thirty articles evaluated US features of hand OA and two assessed US OA features in the foot. There were inconsistencies between studies in terms of what US features were assessed, how these features were defined and what grading system was applied to determine degree of osteoarthritic change. Conclusion: The review found inconsistencies in the definition of synovial pathology. Consequently, it is unclear whether synovial pathology is best represented as separate entities or combined as a single domain, termed "synovitis". How OA US features were defined and graded has largely been extrapolated from recommendations originally constructed for populations with rheumatoid arthritis (RA). Given the prognostic value of synovitis for OA progression and the reduced degree of inflammation experienced in OA compared to RA, the validity of applying definitions, grading systems and atlases originally developed for inflammatory arthritis needs consideration.

Indexed as

OsteoarthritisPeripheral jointsUltrasound imaging

Identifiers

PMID36474810
PMCPMC9718269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.