Evidence map›Paper›PMID 36474793›Full record

ArticleOsteoarthritis and cartilage open2022

Recommendations for weight management in osteoarthritis: A systematic review of clinical practice guidelines.

Yuan Z Lim, Jeffrey Wong, Sultana Monira Hussain, Mahnuma Mahfuz Estee, Luigi Zolio, Matthew J Page, Cheryce L Harrison, Anita E Wluka, Yuanyuan Wang, Flavia M Cicuttini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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  5. Cross-Linked Versus Linear Hyaluronic Acid for Cartilage Repair in Rat Post-Traumatic Osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuan Z LimSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Jeffrey WongSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Sultana Monira HussainSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Mahnuma Mahfuz EsteeSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Luigi ZolioAlfred Health, Melbourne, VIC 3004, Australia.
Matthew J PageSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Cheryce L HarrisonMonash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Anita E WlukaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Yuanyuan WangSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Flavia M CicuttiniSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Monash University · AUAlfred Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: While targeting obesity is central to osteoarthritis management, recent meta-analyses demonstrate only modest effects of weight loss on symptoms, and little on structure. The World Health Organisation recommends that effective management of obesity include prevention of weight gain, weight maintenance and weight loss. Therefore, we systematically reviewed the recommendations and approaches for management of obesity in clinical practice guidelines (CPGs) for osteoarthritis. Design: Nine databases were searched (01.01.2010-15.03.2022) to identify guidelines informing the non-pharmacological management of osteoarthritis. Three reviewers appraised guidelines according to the AGREE II instrument, and independently extracted data on their characteristics. One author extracted and summarised guideline recommendations on weight management. This systematic review is registered on PROSPERO (CRD42021274195). Results: Of the included fifteen CPGs (median AGREE II domain score 78.7%), weight loss was recommended for knee (12 of 13) and hip (10 of 11) but not hand (0 of 4) osteoarthritis. Combination approaches of diet and/or exercise were recommended for overweight or obese individuals in knee (8 of 12) and hip (4 of 10) osteoarthritis. Two guidelines specified ≥5% weight loss. One guideline specified strategies for maintenance of lost weight; none specifically recommended preventing weight gain. There was discordance between strength of recommendation for weight loss and level of evidence (3 of 15). Conclusion: Most CPGs for knee and hip osteoarthritis recommend weight loss to manage obesity in osteoarthritis. As steady weight accumulation is common in adults, preventing weight gain should also be considered as it is a missed opportunity to improve outcomes in osteoarthritis.

Indexed as

Clinical practice guidelinesOsteoarthritisRecommendationSystematic reviewWeight management

Identifiers

PMID36474793
PMCPMC9718266
OpenAlexW4289861023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.