Evidence map›Paper›PMID 36474585›Full record

ArticleOsteoarthritis and cartilage open2020

Course and predictors of upper leg muscle strength over 48 months in subjects with knee osteoarthritis: Data from the osteoarthritis initiative.

A H de Zwart, M van der Leeden, L D Roorda, M van der Esch, J W R Twisk, W F Lems, J Dekker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

A H de ZwartAmsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands.
M van der LeedenAmsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands.
L D RoordaAmsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands.
M van der EschAmsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands.
J W R TwiskAmsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.
W F LemsAmsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands.
J DekkerAmsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.
Reade · NLVrije Universiteit Amsterdam · NLAmsterdam University Medical Centers · NLAmsterdam University of Applied Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Weakness of upper leg muscles has a negative impact on future disease and functional status in subjects with knee osteoarthritis (OA). The aims of the present study were to (i) describe the course of muscle strength over 48 months and (ii) identify baseline predictors for a decline in upper leg muscle strength over time in subjects with knee OA. Methods: Data were obtained from the Osteoarthritis Initiative (OAI) database, a multicenter, observational study of knee OA. Upper leg muscle strength (in N/kg) was measured at baseline, 24 and 48 months. Potential baseline predictors included demographics, OA-specific and health and lifestyle related factors. Linear mixed model analyses were performed. Results: A total of 1390 subjects with knee osteoarthritis were included. A statistically significant decline of muscle strength was found between baseline and 24 months ( Conclusions: Muscle strength declined over time in subjects with knee OA. The identified predictors may help clinicians to select and treat subjects with knee OA at risk of a decline in muscle strength.

Indexed as

CourseKnee jointMuscle strengthOsteoarthritisPredictors

Identifiers

PMID36474585
PMCPMC9718242
OpenAlexW3006449867

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.