Evidence map›Paper›PMID 36474559›Full record

ArticleOsteoarthritis and cartilage open2020

Psychometric properties of the Neuropathic Pain Scale (NPS) in a knee osteoarthritis population.

Emma C Lape, Faith Selzer, Aileen M Davis, Jamie E Collins, Elena Losina, Jeffrey N Katz

Abstract read
In one paragraph

Article in Osteoarthritis and cartilage open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Emma C LapeOrthopaedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, MA, USA.
Faith SelzerOrthopaedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, MA, USA.
Aileen M DavisDivision of Health Care and Outcomes Research, Krembil Research Institute, University Health Network, Toronto, Canada.
Jamie E CollinsOrthopaedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, MA, USA.
Elena LosinaOrthopaedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, MA, USA.
Jeffrey N KatzOrthopaedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Symptoms resembling neuropathic pain (neuropathic-like symptoms) are prevalent in osteoarthritis (OA) populations. Scales that measure neuropathic-like symptoms frequently were established in groups with true neuropathic pain conditions and have not been assessed in OA. We assessed the psychometric properties of the Neuropathic Pain Scale (NPS) in subjects with OA undergoing total knee replacement (TKR). Design: In a prospective study of adults undergoing TKR for OA, we assessed baseline distributions, acceptability (completion rate), internal consistency (Cronbach's alpha), responsiveness 12 months post-TKR, and construct validity of the NPS. We performed factor analysis and created subscales from the items loading onto each retained factor. We evaluated subscale properties and calculated the proportion of total scores attributable to each subscale and compared this with the proportion expected if each item contributed equally. Results: Mean baseline NPS score among 263 participants was 42.7 (SD: 15.9). Cronbach's alpha was 0.88. Factor analysis produced two factors: "bothersome" (items: intense/sharp/dull/unpleasant/deep; Cronbach's alpha = 0.87), and "dysesthetic" (items: cold/sensitive/itchy/surface; alpha = 0.77). Bothersome items contributed more to total NPS scores (74%) than would be expected if each item contributed equally (50%). NPS scores correlated moderately with baseline pain and function, and decreased after TKR, with standardized response means (SRMs) of: total NPS: 1.77, Bothersome subscale: 2.03, Dysesthetic subscale: 0.70. Conclusions: The NPS had acceptable completion, internal consistency, and construct validity, but was not optimal for use in OA; Bothersome subscale items disproportionately drive total NPS scores and may fail to discriminate between nociceptive and neuropathic-like symptoms.

Indexed as

Neuropathic painOsteoarthritisPsychometric propertiesTotal knee replacementValidation

Identifiers

PMID36474559
PMCPMC9718093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.