ArticleInternational journal of nanomedicine2022
Stability, Toxicity, and Antibacterial Potential of Gallic Acid-Loaded Graphene Oxide (GAGO) Against Methicillin-Resistant
Article in International journal of nanomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Solvent-Dependent Efficacy ofTropical life sciences research · 2026Article
- Graphene-based nanomaterials: mechanisms and potentials in the fight against multidrug resistant bacterial infections: a review.RSC advances · 2025Review
- Gallic Acid-Modified Graphene Oxide Nanocomposites Based Photothermal-Chemotherapy Enhancing Melanoma Immunotherapy.International journal of nanomedicine · 2025Article
- Effect of Graphene Aerosol Doped with Hypochlorous Acid, Curcumin, and Silver Nanoparticles on Selected Structural and Biological Properties.Materials (Basel, Switzerland) · 2024Article
- Photodynamic Antibacterial Therapy of Gallic Acid-Derived Carbon-Based Nanoparticles (GACNPs): Synthesis, Characterization, and Hydrogel Formulation.Pharmaceutics · 2024Article
- Protective Roles and Therapeutic Effects of Gallic Acid in the Treatment of Cardiovascular Diseases: Current Trends and Future Directions.Current medicinal chemistry · 2024Review
- An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent.Food science & nutrition · 2023Review
- Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine.Nanomaterials (Basel, Switzerland) · 2023Review
- Management and Mitigation of Vibriosis in Aquaculture: Nanoparticles as Promising Alternatives.International journal of molecular sciences · 2023Review
- Polymyxin B complexation enhances the antimicrobial potential of graphene oxide.Frontiers in cellular and infection microbiology · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impetuous usage of antibiotics has led to the perpetual rise of methicillin-resistant Purpose: The present study investigates the stability, toxicity, and antibacterial potential of gallic acid-loaded graphene oxide (GAGO) on several MRSA strains. Methods: The stability of a synthesized and characterized GAGO was monitored in different physiological media. The toxicity profile of GAGO was evaluated in 3T3 murine fibroblast cells and the embryonic zebrafish model. The antibacterial activity of GAGO against MRSA, methicillin-susceptible Results: A stable GAGO nanocomposite has shown an improved toxicity profile in 3T3 murine fibroblast cells and zebrafish embryos, besides exhibiting normal ROS levels than graphene oxide (GO) and GA (gallic acid). The nanocomposite inhibited the growth of all bacterial strains employed. The effectiveness of the GAGO nanocomposite was comparable to cefoxitin (CFX), at ≥150 µg/mL in MRSA and MSSA. GAGO exhibited a significantly delayed response towards MRSA- Conclusion: In summary, the present study indicates the antibacterial potential of GAGO against MRSA strains, but further study is warranted to understand the mechanism of action of GAGO and its resistance in MRSA strains.
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