Evidence map›Paper›PMID 36474507›Full record

ReviewOncoTargets and therapy2022

Licorice (

Hardeep Singh Tuli, Vivek Kumar Garg, Jinit K Mehta, Ginpreet Kaur, Ranjan K Mohapatra, Kuldeep Dhama, Katrin Sak, Ajay Kumar, Mehmet Varol, Diwakar Aggarwal and 5 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in OncoTargets and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Plants (Basel, Switzerland) · 2026
    Article
  4. Formulation and Biological Evaluation ofAntioxidants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Polyphenolic compounds inFrontiers in pharmacology · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 6 countries.

Hardeep Singh TuliDepartment of Biotechnology, Maharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to Be University), Mullana-Ambala, Haryana, India.
Vivek Kumar GargDepartment of Medical Lab Technology, University Institute of Applied Health Sciences, Chandigarh University, Mohali, Punjab, India.
Jinit K MehtaDepartment of Pharmacology, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, Shri Vile Parle Kelavani Mandal, Narsee Monjee Institute of Management Studies, Mumbai, Maharashtra, India.ORCID 0000-0002-6652-6342
Ginpreet KaurDepartment of Pharmacology, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, Shri Vile Parle Kelavani Mandal, Narsee Monjee Institute of Management Studies, Mumbai, Maharashtra, India.
Ranjan K MohapatraDepartment of Chemistry, Government College of Engineering, Keonjhar, Odisha, India.
Kuldeep DhamaDivision of Pathology, Indian Council of Agricultural Research-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh, India.ORCID 0000-0001-7469-4752
Katrin SakNGO Praeventio, Tartu, Estonia.ORCID 0000-0003-0736-2525
Ajay KumarDepartment of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, India.
Mehmet VarolDepartment of Molecular Biology and Genetics, Faculty of Science, Mugla Sitki Kocman University, Mugla, Turkey.
Diwakar AggarwalDepartment of Biotechnology, Maharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to Be University), Mullana-Ambala, Haryana, India.
Uttpal AnandDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Jagjit KaurCentre of Excellence in Nanoscale Biophotonics, Graduate School of Biomedical Engineering, Faculty of Engineering, The University of New South Wales, Sydney, Australia.
Ross GillanCollege of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, FL, USA.
Gautam SethiDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Anupam BishayeeCollege of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, FL, USA.ORCID 0000-0001-9159-960X
Lake Erie College of Osteopathic Medicine · USMaharishi Markandeshwar University, Mullana · INNarsee Monjee Institute of Management Studies · INBen-Gurion University of the Negev · ILChandigarh University · INGovernment College of Engineering, Keonjhar · INGuru Nanak Dev University · INIndian Council of Agricultural Research · INMuğla University · TRNational University of Singapore · SGUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over the past few decades. Although chemotherapeutics and surgery are widely used in clinical settings, they are often insufficient to provide the cure for cancer patients. Hence, more effective treatment options are highly needed. Although licorice has been used as a medicinal herb since ancient times, the knowledge about molecular mechanisms behind its diverse bioactivities is still rather new. In this review article, different anticancer properties (antiproliferative, antiangiogenic, antimetastatic, antioxidant, and anti-inflammatory effects) of various bioactive constituents of licorice (

Indexed as

angiogenesisapoptosiscancercell cyclelicoricenano-deliverytreatment

Identifiers

PMID36474507
PMCPMC9719702
OpenAlexW4310348451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.