ReviewJournal of microbiology and biotechnology2023
The Effects of Protein and Supplements on Sarcopenia in Human Clinical Studies: How Older Adults Should Consume Protein and Supplements.
Review in Journal of microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Enhancing Muscle Quality: Exploring Leucine and Whey Protein in Sarcopenic Individuals.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Improving sarcopenia in older adults: a systematic review and meta-analysis of randomized controlled trials of whey protein supplementation with or without resistance training.The journal of nutrition, health & aging · 2024Pooled it
- Age at menopause and risk of sarcopenia in postmenopausal women: evidence from the China health and retirement longitudinal study.Reproductive health · 2026Article
- A Contemporary Perspective on Long-Term Complications of Bariatric Surgery.Obesity surgery · 2026Review
- Sarcopenia in Aging: Pathogenesis, Diagnosis, and Emerging Therapeutic Frontiers.Molecular imaging and biology · 2026Review
- Exploring the Impact of Extended Amino Acid Supplementation on Body Composition and Psychopathology in Patients with Eating Disorders Undergoing Psycho-Nutritional RehabilitationEndocrine, metabolic & immune disorders drug targets · 2026Article
- Content and framing analysis of food supplement in the BBC news and evaluation from a nutrition science perspective.Frontiers in nutrition · 2026Article
- Osteosarcopenia in older adults undergoing transcatheter aortic valve replacement: A narrative review of mortality and frailty implications.World journal of cardiology · 2025Review
- Nonessential amino acid is not nonessential in geriatric patients: implications for maxillofacial wound healing and bone repair.Maxillofacial plastic and reconstructive surgery · 2025Review
- Sarcopenia and its associated factors among hip fracture patients admitted to a North African (Egyptian) Level one trauma center, a cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- A Comprehensive Review of the Correlations of Measurement Parameters among Modern Technologies for Sarcopenia Assessment.Aging and disease · 2025Review
- Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia.Current nutrition reports · 2025Review
- Dietary advanced glycation end-products exacerbate sarcopenia onset by activating apoptosis through PRMT1-mediated CRTC3 arginine methylation.Cellular and molecular life sciences : CMLS · 2025Article
- Predictive model for sarcopenia in patients with non-small cell lung cancer and malignant pleural effusion.BMC cancer · 2025Article
- Article
- Sarcopenic Obesity: A Comprehensive Approach for Postmenopausal Women.Journal of menopausal medicine · 2024Review
- Effects of a Multicomponent Preventive Intervention in Women at Risk of Sarcopenia: A Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
- Immune aging: biological mechanisms, clinical symptoms, and management in lung transplant recipients.Frontiers in transplantation · 2024Review
- Unveiling the Knowledge Frontier: A Scientometric Analysis of COPD with Sarcopenia.International journal of chronic obstructive pulmonary disease · 2024Article
- Benefits and side effects of protein supplementation and exercise in sarcopenic obesity: A scoping review.Nutrition journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia is a condition in which muscle mass, strength, and performance decrease with age. It is associated with chronic diseases such as diabetes, cardiovascular disease, and hypertension, and contributes to an increase in mortality. Because managing sarcopenia is critical for maintaining good health and quality of life for the elderly, the condition has sparked concern among many researchers. To counteract sarcopenia, intake of protein is an important factor, while a lack of either protein or vitamin D is a major cause of sarcopenia. In addition, essential amino acids, leucine, β-hydroxy β-methylbutyrate (HMB), creatine, and citrulline are used as supplements for muscle health and are suggested as alternatives for controlling sarcopenia. There are many studies on such proteins and supplements, but it is necessary to actually organize the types, amounts, and methods by which proteins and supplements should be consumed to inhibit sarcopenia. In this study, the efficacy of proteins and supplements for controlling sarcopenia according to human clinical studies is summarized to provide suggestions about how the elderly may consume proteins, amino acids, and other supplements.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.