ArticleBMC psychiatry2022
Association between dietary theobromine with depression: a population-based study.
Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.Medicine · 2025Observational
- Association between dietary intake and urinary concentrations of caffeine and caffeine metabolites and elevated serum prostate-specific antigen (PSA) among men at risk for prostate cancer.Cancer causes & control : CCC · 2025Article
- Association between dietary theobromine and age-related macular degeneration: results from NHANES 2005-2008 and in vitro experiments.European journal of medical research · 2025Article
- Association between Life's Essential 8 and depression: a population-based study.Archives of medical science : AMS · 2025Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study is to investigate the possible link between dietary theobromine intake and symptoms of depression. MATERIALS AND
methodsThese results are based on the responses of 3637 people who took part in the National Health and Nutrition Examination Survey in 2017-2018. Participants' daily theobromine intake was determined using a 24-h food questionnaire from the 2017-2018 cycle. Presence of depression was defined as a score of 5 or above on the Patient Health Questionnaire. Association between theobromine intake and depression was examined using a multivariate logistic regression adjusting for several relevant sociodemographic, lifestyle and health-related factors.
resultsA total of 6903 participants were included in the study. The results of multivariate logistic regression showed a correlation between depressive symptoms and theobromine intake (OR:1.17, 95%CI:1.02-1.34).
conclusionsOur cross-sectional population based study suggests that increased theobromine intake is associated with increased risk for depression. Nevertheless, more investigations are needed to confirm our findings.
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