Evidence map›Paper›PMID 36474125›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Application of the long axial field-of-view PET/CT with low-dose [

Christos Sachpekidis, Leyun Pan, Annette Kopp-Schneider, Vivienn Weru, Jessica C Hassel, Antonia Dimitrakopoulou-Strauss

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Clinical evaluation of deep learning-based CT-free PET reconstruction image: a dual-center study.European journal of nuclear medicine and molecular imaging · 2026
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  4. Lesion conspicuity by size in [EJNMMI research · 2026
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  6. Lymphoma Therapy Response Assessment with Low-Dose [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
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  7. Advances in Positron Emission Tomography/Computed Tomography for Diagnosing and Managing Primary Posterior Uveal Melanoma.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Low-activity [EJNMMI physics · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Combined whole-body dynamic and static PET/CT with low-dose [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christos SachpekidisClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, 69210, Heidelberg, Germany. christos_saxpe@yahoo.gr.ORCID 0000-0001-8739-8741
Leyun PanClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
Annette Kopp-SchneiderDepartment of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Vivienn WeruDepartment of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jessica C HasselDepartment of Dermatology, Skin Cancer Center, University Hospital Heidelberg, Heidelberg, Germany.
Antonia Dimitrakopoulou-StraussClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
German Cancer Research Center · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe recent introduction of long axial field-of-view (LAFOV) PET/CT scanners has yielded very promising results regarding image quality and sensitivity in oncological patients. We, herein, aim to determine an appropriate acquisition time range for the new long axial field of view Biograph Vision Quadra PET/CT (Siemens Healthcare) using low dose [ METHODOLOGY: Forty-nine melanoma patients were enrolled in the study. All patients underwent total body PET/CT from the top of the head through the feet in two bed positions (field-of-view 106 cm) after i.v. injection of 2.0 MBq/kg [

resultsA total of 60 scans were evaluated. Concerning visual analysis, 49/60 (81.7%) PET-10 scans were pathological, while the respective frequencies were 49/60 (81.7%) for PET-8 (95%-CI: - 0.0602-0.0602), 49/60 (81.7%) for PET-6 (95%-CI: - 0.0602-0.0602), 48/60 (80%) for PET-5 (95%-CI: - 0.0445-0.0886), 46/60 (76.7%) for PET-4 (95%-CI: - 0.0132-0.1370), and 45/60 (75%) for PET-2 (95%-CI: 0.0025-0.1593). In 18 PET-10 scans, the extent of metastatic involvement was very large, rendering the accurate calculation of [

conclusionsIn melanoma, low-dose LAFOV PET/CT imaging is feasible and can reduce the total scan time from head to upper thigh up to 5 min providing comparable diagnostic data to standard lengths of acquisition. This may have significant implications for the diagnostic work-up of patients with melanoma, given the need for true whole-body imaging in this type of cancer.

Indexed as

MelanomaPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18HumansPositron-Emission TomographyTime FactorsFluorodeoxyglucose F18[18F]FDGLAFOV PET/CTMelanomaSUVTotal bodyWhole-body

Identifiers

PMID36474125
PMCPMC9931831
OpenAlexW4311702769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.