Evidence map›Paper›PMID 36473987›Full record

ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Updates of ocular involvement in granulomatosis with polyangiitis.

Lin Mei, Luoziyi Wang, Hong Yan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Rare Case of Limited Granulomatosis with Polyangiitis Presenting as Bilateral Parotitis.European journal of case reports in internal medicine · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lin MeiShaanxi Eye Hospital, Xi'an People's Hospital, Affiliated Xi'an Fourth Hospital, Northwestern Polytechnical University, Xi'an, 710004, China.
Luoziyi WangDepartment of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, 200040, China.
Hong YanShaanxi Eye Hospital, Xi'an People's Hospital, Affiliated Xi'an Fourth Hospital, Northwestern Polytechnical University, Xi'an, 710004, China. yan2128ts@hotmail.com.ORCID http://orcid.org/0000-0001-7521-1636
Northwestern Polytechnical University · CNFudan University · CN

Funding

Xi'an Talent Program XAYC200021
6 · The paper itself

Abstract

Granulomatosis with polyangiitis (GPA) is a systemic inflammatory disease characterized by necrotizing vasculitis of the small-to-medium-sized vessels. GPA results from irregular autoimmune response with elevation of anti-neutrophil cytoplasmic antibody (ANCA) and inflammatory damage of vascular endothelial cells and other tissues. Ocular involvement is common in GPA with various manifestations due to the different ocular tissues suffered, but mostly, it causes orbital mass, dacryocystitis, scleritis, conjunctivitis, and keratitis. The diagnosis of GPA is based on a comprehensive analysis of systemic manifestations of vasculitis, imaging examinations, laboratory test especially serum levels of ANCA, and histological biopsy. Immunosuppressive therapy has greatly lowered the mortality and improved the prognosis of GPA, and the emergence of biological therapy indicates a promising prospect for GPA treatment strategy. In this narrative review, we integrate the latest literature on GPA-induced ocular disorders, presenting the previous views and new understandings especially on epidemiology, etiology, molecular mechanism, clinical manifestation, diagnosis, and treatment of GPA-related ocular involvement.

Indexed as

Eye DiseasesGranulomatosis with PolyangiitisOrbital DiseasesAntibodies, Antineutrophil CytoplasmicEndothelial CellsHumansAntibodies, Antineutrophil CytoplasmicBiological therapyGranulomatosis with polyangiitisOrbital granulomaScleritis

Identifiers

PMID36473987
OpenAlexW4311683512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.