SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023
Opening- and closing-wedge high tibial osteotomy are comparable and early full weight bearing is safe with angular stable plate fixation: a meta-analysis.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Risk Factors and Clinical Outcomes of Osteotomy Plane Violation by D-Hole Screws in Medial Open Wedge High Tibial Osteotomy: A Simulation and Comparative Study.Medicina (Kaunas, Lithuania) · 2023Trial
- Smoking and lateral hinge fracture are associated with delayed union at 6 months in open wedge distal tibial tuberosity osteotomy.Journal of experimental orthopaedics · 2026Article
- High Tibial Osteotomy for Knee Osteoarthritis with Genu Varum: A Retrospective, Observational Study.Journal of functional morphology and kinesiology · 2026Article
- [Application progress of customized steel plates in osteotomy and orthopedic treatment of knee osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Review
- High survival rates and patient satisfaction 12 years after medial open wedge high tibial osteotomy surgery: A prospective cohort study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Reinforced locking screws with enhanced head and neck junction: improving biomechanical stability in opening-wedge high tibial osteotomy applications.Journal of orthopaedic surgery and research · 2025Article
- Double-level knee valgization osteotomy has high survivorship and a low complication rate in a single-center series of 58 cases with a mean clinical follow-up of 10 years.Knee surgery & related research · 2025Article
- Appropriate hinge position to prevent hinge fracture in open wedge distal tuberosity tibial osteotomy.Journal of experimental orthopaedics · 2025Article
- Knee osteotomies are becoming widely accepted and increasingly used, but rehabilitation techniques still vary widely between surgeons: A survey on current trends.Journal of experimental orthopaedics · 2025Article
- Comparative impact of high tibial osteotomy and supramalleolar osteotomy on limb alignment and ankle function: a retrospective study.Journal of orthopaedic surgery and research · 2025Article
- Fixation stability and stress redistribution following metal block use in opening-wedge high tibial osteotomy: a finite element analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Positive Results Using Variable Fixation in Medial Opening Wedge High Tibial Osteotomies in Patients with Unilateral Knee Osteoarthritis: An Observational Clinical Investigation.Journal of clinical medicine · 2024Article
- Biomechanical evaluation of a newly designed locking plate for opening wedge high tibial osteotomy: stress distribution and stability in the presence of lateral hinge fracture.Journal of orthopaedic surgery and research · 2024Article
- Clinical outcome after open-wedge high tibial osteotomy: comparison of double-triangle locking compression plate (DT-LCP) and T-shaped locking compression plate (T-LCP).BMC musculoskeletal disorders · 2024Article
- Article
- Postoperative management following osteotomies around the knee: a narrative review.EFORT open reviews · 2024Review
- Medial Closing Wedge High Tibial Osteotomy Accurately Corrects Genu Valgum without Iatrogenic Deformity or Complications: A Consecutive Series of Thirty-one Procedures.Strategies in trauma and limb reconstructionArticle
- Medial Opening-Wedge High Tibial Osteotomy.JBJS essential surgical techniquesArticle
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to establish the gold standard for surgical technique, fixation, and rehabilitation for HTO in patients with unicompartmental knee osteoarthritis.
methodsMedline, Embase, and SPORTDiscus databases were searched up to April 2022. Included were (1) randomized controlled trials (RCTs) comparing opening-wedge HTO (owHTO) and closing-wedge HTO (cwHTO), (2) biomechanical studies and prospective patient studies comparing biomechanical and clinical results for plate fixators, and (3) RCTs comparing an early versus delayed full-weight-bearing (FWB) protocol.
resultsThe pooled results for the surgical technique showed no significant differences between owHTO and cwHTO for most PROMs on pain, activity, and risk for conversion to TKA. The cwHTO group showed a slightly better improvement in KOOS/WOMAC pain scores (4.51; 95% CI 1.18-7.85), and a significantly lower change in posterior tibial slope (p = 0.03). The pooled results for the fixation method showed the highest force at maximum failure for the Activmotion (Newclip Technics, France), Aescula (B. Braun Korea, Korea), 2nd generation Puddu (Arthrex Inc., USA), and TomoFix plate (Depuy Synthes, Switzerland). The pooled results for the rehabilitation protocol showed no significant differences between the early full-weight-bearing (FWB) group and the delayed FWB group for functional scores, complication rates, and delayed unions.
conclusionBoth owHTO and cwHTO reduced pain and improved knee function. Locking plate fixation should be used for owHTO. An early FWB protocol has proven to be safe in patients with small corrections, no hinge fractures, and non-smokers. LEVEL OF EVIDENCE: Level II.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.