ArticleNature communications2022
The overlapping burden of the three leading causes of disability and death in sub-Saharan African children.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A landscape analysis of clinical trials and infant clinical trials in Kenya, Ethiopia, and Nigeria.Frontiers in epidemiology · 2024Pooled it
- Zoonotic Parasite Nanovaccines: Progress, Challenges, and Future Perspectives.Integrative zoology · 2026Review
- Artificial intelligence-enabled pediatric radiology in low-resource settings: addressing resource constraints in the African healthcare system.Pediatric radiology · 2026Review
- Article
- Co-Occurrence of Malaria, Pneumonia, and Diarrheal Disease Among Households: A Cohort Study in Rural Western Uganda.Tropical medicine & international health : TM & IH · 2026Article
- Global burden of antimicrobial-resistant Staphylococcus aureus lower respiratory tract infections in older adults: a secondary analysis of the MICROBE database (1990-2021).BMC infectious diseases · 2026Article
- Understanding the burden and distribution of health conditions in Zambia's school-aged population: evidence from the school health programme.BMC public health · 2026Article
- Quantifying the fatal and non-fatal burden of disease associated with child growth failure, 2000-2023: a systematic analysis from the Global Burden of Disease Study 2023.The Lancet. Child & adolescent health · 2026Article
- Assessing heat exposure and its effects on farmer health, harvest yields, and nutrition: a study protocol for Burkina Faso and Kenya.Global health action · 2025Article
- Serological assessment of pediatric parasite exposure in two Senegalese districts using multiplex serology.Current research in parasitology & vector-borne diseases · 2025Article
- Global burden of viral skin diseases from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.Frontiers in public health · 2025Article
- Community responses to a novel house design: A qualitative study of "Star Homes" in Mtwara, southeastern Tanzania.PloS one · 2025Article
- Are There Benefits to Breastfeeding for Long Durations That Continue after Breastfeeding Has Stopped? An Analysis of Acute Respiratory Illness in Nigerian Children.Children (Basel, Switzerland) · 2024Article
- Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.Lancet (London, England) · 2024Article
- Challenges Locating the Scene of Emergency: A Qualitative Study of the EMS System in Rwanda.Prehospital emergency care · 2024Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseases, while others had one or two dominant sources of unit-level burden, with no consistent pattern geographically across the entire subcontinent. Using a subnational counterfactual analysis, we show that nearly 300 million DALYs could have been averted since 2000 by raising all units to their national average. Our findings are directly relevant for decision-makers in determining which and targeting where the most appropriate interventions are for increasing child survival.
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