Evidence map›Paper›PMID 36473659›Full record

ArticleThe Science of the total environment2023

Urinary phthalates, phenols, and parabens in relation to sleep health markers among a cohort of Mexican adolescents.

Astrid N Zamora, Karen E Peterson, Martha M Téllez-Rojo, Peter X K Song, John D Meeker, Alejandra Cantoral, Jaclyn M Goodrich, Dana C Dolinoy, Erica C Jansen

Open access · greenAbstract read
In one paragraph

Article in The Science of the total environment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Role of sleep in asthenospermia induced by di (2-ethyl-hexyl) phthalate.Environmental science and pollution research international · 2024
    Article
  9. Predictors of Phthalate Metabolites Exposure among Healthy Pregnant Women in the United States, 2010-2015.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Astrid N ZamoraDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA; Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Martha M Téllez-RojoCenter for Research on Nutrition and Health, National Institute of Public Health, Cuernavaca, Mexico.
Peter X K SongDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
John D MeekerDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Alejandra CantoralHealth Department, Ibero-American University, Mexico City, Mexico.
Jaclyn M GoodrichDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Dana C DolinoyDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA; Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Erica C JansenDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA; Department of Neurology, Division of Sleep Medicine, Michigan Medicine, Ann Arbor, MI, USA. Electronic address: janerica@umich.edu.
University of Michigan–Ann Arbor · USIbero American University · MXInstituto Nacional de Salud Pública · MX

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson · 2010 to 2026
$20.3M
Environmental Epigenomics and Precision Environmental HealthR35ES031686 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2020 to 2026
$6.1M
Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PADMANABHAN, VASANTHA, PETERSON, KAREN EILEEN · 2013 to 2018
$3.9M
Cardiovascular and Chronic Disease Prevention Training ProgramT32HL161270 · NHLBI · STANFORD UNIVERSITY · PI CHRISTOPHER D GARDNER · 2022 to 2026
$2.6M
E3Gen: Multigenerational Influences of Social Structure on Toxicant Exposures and Life Course Health in the ELEMENT CohortR24ES028502 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson, Peter Xuekun Song · 2017 to 2026
$2.2M
Sleep and Circadian Rhythms in Adolescence: Epigenetic Pathways of Cardiometabolic RiskK01HL151673 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JANSEN, ERICA CHRISTINE · 2020 to 2024
$759k
NHLBI NIH HHS K01 HL151673NHLBI NIH HHS T32 HL161270NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P30 ES017885NIEHS NIH HHS R24 ES028502NIEHS NIH HHS R35 ES031686
6 · The paper itself

Abstract

introductionEmerging research has shed light on the potential impact of environmental toxicants on sleep health, however, it remains unclear if these associations exist during adolescence and whether associations differ by sex. This study aimed to examine associations between phthalates, parabens, and phenols on adolescent sleep health using cross-sectional data from 470 participants from the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) study. MATERIAL AND

methodsIn 2015, spot urine samples were analyzed for exposure biomarkers of 14 phthalate metabolites, seven phenol, and four paraben analytes. Over seven consecutive days, sleep duration, midpoint, and fragmentation were assessed with wrist-actigraphy. We examined associations between summary phthalates, individual phthalate metabolites, and phenol and paraben analytes with mean weekday sleep duration, midpoint, and fragmentation using linear regression models adjusted for specific-gravity and sex, age, pubertal status, smoking and alcohol behavior, physical activity, and screen time.

resultsMean (SD) age was 13.8 (2.1) years; 53.5 % were female. Σ Plastic - summary measure for toxicants from plastic sources - and Σ DEHP and its metabolites, were associated with longer sleep duration in the unstratified sample. To illustrate, every 1-unit log increase in Σ DEHP was associated with 7.7 min (95 % CI: 0.32, 15.1; p < 0.05) longer duration. Summary measures of toxicants from plastic sources, personal care products, anti-androgenic toxicants, and multiple individual phthalates, phenols, and parabens were associated with later midpoint. The midpoint associations were largely female-specific. There were no associations with sleep fragmentation.

conclusionsHigher EDC exposure may be related to longer sleep duration and later sleep timing during adolescence, and associations may vary by toxicant and according to sex.

Indexed as

Diethylhexyl PhthalateEndocrine DisruptorsEnvironmental PollutantsPhthalic AcidsAdolescentBenzhydryl CompoundsCross-Sectional StudiesEnvironmental ExposureFemaleHazardous SubstancesHumansMaleMexicoParabensPhenolPhenolsBenzhydryl CompoundsDiethylhexyl PhthalateEndocrine DisruptorsEnvironmental PollutantsHazardous SubstancesParabensPhenolPhenolsphthalic acidPhthalic AcidsAdolescent healthEndocrine-disrupting chemicalsSleep durationSleep healthSleep timing

Identifiers

PMID36473659
PMCPMC9880990
OpenAlexW4311169251

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.