Evidence map›Paper›PMID 36473611›Full record

ArticleJournal of vascular and interventional radiology : JVIR2023

Experimental VX2 Rabbit Liver Tumor Model in Carbon Tetrachloride-Induced Cirrhosis of the Liver.

Jessica G Santana, Annabella Shewarega, David Nam, Vinzent Kahl, David C Madoff, Xuchen Zhang, Julius Chapiro

Open access · greenAbstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jessica G SantanaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Engineering, Yale School of Medicine, New Haven, Connecticut.
Annabella ShewaregaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Radiology, Charité-Universitätsmedizin Berlin, Berlin Institute of Health, Berlin, Germany.
David NamDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Vinzent KahlDepartment of Radiology, Charité-Universitätsmedizin Berlin, Berlin Institute of Health, Berlin, Germany.
David C MadoffDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Xuchen ZhangDepartment of Pathology, Yale School of Medicine, New Haven, Connecticut.
Julius ChapiroDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut. Electronic address: julius.chapiro@yale.edu.
Yale University · USBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DE

Funding

Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI WAJAHAT Zafar MEHAL · 1986 to 2026
$31.1M
Quantitative Multimodal Imaging Biomarkers for Combined Locoregional and Immunotherapy of Liver CancerR01CA206180 · NCI · YALE UNIVERSITY · PI CHAPIRO, JULIUS, DUNCAN, JAMES S · 2016 to 2025
$6.1M
Extracellular pH mapping as therapeutic readout of drug delivery in glioblastomaR01EB023366 · NIBIB · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2017 to 2020
$2.5M
NCI NIH HHS R01 CA206180NIBIB NIH HHS R01 EB023366NIDDK NIH HHS P30 DK034989
6 · The paper itself

Abstract

Liver cirrhosis is a major underlying factor in the development of hepatocellular carcinoma. Currently, there is an unmet need for midsize experimental vertebrate models that would offer reproducible implantable liver tumors in a cirrhotic liver background. This study establishes a protocol for a syngeneic rabbit model of VX2 liver cancer with underlying liver cirrhosis induced using carbon tetrachloride (CCl

Indexed as

Carcinoma, HepatocellularLiver Cirrhosis, ExperimentalLiver NeoplasmsLiver Neoplasms, ExperimentalAnimalsCarbon TetrachlorideLiverLiver CirrhosisMaleRabbitsCarbon Tetrachloride

Identifiers

PMID36473611
PMCPMC11037556
OpenAlexW4310723095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.