Evidence map›Paper›PMID 36473471›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2023

The effect of chemotherapy in sarcomatoid bladder cancer patients treated with radical cystectomy.

Stefano Tappero, Gabriele Sorce, Benedikt Hoeh, Lukas Hohenhorst, Andrea Panunzio, Cristina Cano Garcia, Mattia Piccinelli, Zhe Tian, Stefano Parodi, Francesco Montorsi and 10 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 6 countries.

Stefano TapperoCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Gabriele SorceCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Benedikt HoehCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Lukas HohenhorstCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Andrea PanunzioCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Cristina Cano GarciaCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Mattia PiccinelliCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Zhe TianCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Stefano ParodiDepartment of Urology, IRCCS Policlinico San Martino, Genova, Italy.
Francesco MontorsiDivision of Experimental Oncology/Unit of Urology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Felix K H ChunDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.
Markus GraefenMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Alessandro AntonelliDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Fred SaadCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Shahrokh F ShariatDepartment of Urology, Weill Cornell Medical College, New York, NY, United States.
Ottavio De CobelliDepartment of Urology, IEO European Institute of Oncology, IRCCS, Milan, Italy.
Nazareno R SuardiDepartment of Urology, Spedali Civili of Brescia, Brescia, Italy.
Marco BorghesiDepartment of Urology, IRCCS Policlinico San Martino, Genova, Italy.
Carlo TerroneDepartment of Urology, IRCCS Policlinico San Martino, Genova, Italy.
Pierre I KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, Université de Montréal Health Centre, Montreal, QC, Canada.
Université de Montréal · CAGoethe University Frankfurt · DEIstituti di Ricovero e Cura a Carattere Scientifico · ITMartini-Klinik · DEMcGill University Health Centre · CAUniversity of Genoa · ITUniversity of Verona · ITAl-Ahliyya Amman University · JOAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleOspedale Policlinico San Martino · ITUniversity Hospital Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionData about the role of chemotherapy in sarcomatoid bladder cancer (SBC) are limited. We addressed the effect of chemotherapy in non-metastatic SBC patients treated with radical cystectomy (RC).

methodsUsing the Surveillance, Epidemiology, and End Results database (2001-2018), we identified 331 patients with non-metastatic muscle-invasive or higher SBC (T

resultsOf 331 SBC patients, 129 (38.9%) were exposed to chemotherapy. The rate of organ-confined stage (T

conclusionsIn non-metastatic SBC treated with RC, the association between chemotherapy and lower CSM is particularly strong in organ-confined stage. A substantially larger cohort would be required to confirm the statistical significance of the recorded protective effect of chemotherapy.

Identifiers

PMID36473471
PMCPMC10027350
OpenAlexW4308173056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.