Observational studyRespiratory medicine and research2023
One-year mortality in COVID-19 is associated with patients' comorbidities rather than pneumonia severity.
Observational study in Respiratory medicine and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 25 citations in OpenAlex.
- Pulmonary Function and Survival 1 Year After Dupilumab Treatment of Acute Moderate to Severe Coronavirus Disease 2019: A Follow-up Study From a Phase 2a Trial.Open forum infectious diseases · 2024Trial
- Immune risk phenotype and long-term mortality after community-acquired pneumonia in older adults: clinical and immune determinants.Immunity & ageing : I & A · 2026Article
- Post-discharge mortality among SARS-CoV-2-infected adult patients with severe acute respiratory infection in Bangladesh (2020-2023): burden, clinical characteristics, and associated risk factors.Tropical medicine and health · 2026Article
- Longer term post-hospital morbidity and mortality following admission with COVID-19: a systematic review and meta-analysis.ERJ open research · 2025Article
- Association of COPD With Clinical Outcomes After Hospital Admission in SARS-CoV-2 Patients During the Omicron Variant Period: A Retrospective Cohort Study.The clinical respiratory journal · 2025Article
- Imaging and Laboratory Results as Predictors of the Course of COVID-19.Advances in respiratory medicine · 2025Article
- COVID-19 and risk of long-term mortality in COPD: a nationwide population-based cohort study.BMJ open respiratory research · 2025Article
- Observational
- Mortality and COVID Infection: Predictors of Mortality 10 Months after Discharge.Diseases (Basel, Switzerland) · 2024Article
- Long-term mortality of Dutch COVID-19 patients admitted to the intensive care medicine: a retrospective analysis from a national quality registry.Critical care science · 2024Article
- Risk factors for the in‑hospital and 1‑year mortality of elderly patients hospitalized due to COVID‑19‑related pneumonia.Experimental and therapeutic medicine · 2024Article
- Post-discharge all-cause mortality in COVID-19 recovered patients hospitalized in 2020: the impact of chronic kidney disease.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024Article
- Functional Status in Older Adults following Hospitalization for COVID-19: A Cohort Study.Annals of geriatric medicine and research · 2023Article
- [Impacto de la dependencia funcional de los pacientes mayores atendidos en los servicios de Urgencias españoles durante la primera ola pandémica de la COVID-19 sobre la mortalidad a 30, 180 y 365 días en función del diagnóstico (COVID versus no COVID).]Revista espanola de salud publica · 2023Observational
- Determinants of post discharge mortality among hospitalized COVID-19 patients.The Indian journal of medical research · 2023Article
- Hospitalized COVID-19 patients with diabetes have an increased risk for pneumonia, intensive care unit requirement, intubation, and death: A cross-sectional cohort study in Mexico in 2020.Health science reports · 2023Article
- Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study.EClinicalMedicine · 2023Article
- The Very Long COVID: Persistence of Symptoms after 12-18 Months from the Onset of Infection and Hospitalization.Journal of clinical medicine · 2023Article
- Persistent Respiratory Failure and Re-Admission in Patients with Chronic Obstructive Pulmonary Disease Following Hospitalization for COVID-19.International journal of chronic obstructive pulmonary disease · 2023Observational
- Predictors of early and long-term mortality after ICU discharge in critically ill COVID-19 patients: A prospective cohort study.PloS one · 2023Article
Corrections and comments
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Authors and funding
29 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn patients with pneumonia or acute respiratory distress syndrome who survived hospitalization, one-year mortality can affect up to one third of discharged patients. Therefore, significant long-term mortality after COVID-19 respiratory failure could be expected. The primary outcome of the present study was one-year all-cause mortality in hospitalized COVID-19 patients.
methodsObservational study of COVID-19 patients hospitalized at Papa Giovanni XXIII Hospital (Bergamo, Italy), during the first pandemic wave.
resultsA total of 1326 COVID-19 patients were hospitalized. Overall one-year mortality was 33.6% (N 446/1326), with the majority of deaths occurring during hospitalization (N=412, 92.4%). Thirty-four patients amongst the 914 discharged (3.7%) subsequentely died within one year. A third of these patients died for advanced cancer, while death without a cause other than COVID-19 was uncommon (8.8% of the overall post-discharge mortality). In-hospital late mortality (i.e. after 28 days of admission) interested a population with a lower age, and fewer comorbidities, more frequentely admitted in ICU. Independent predictors of post-discharge mortality were age over 65 years (HR 3.19; 95% CI 1.28-7.96, p-value=0.013), presence of chronic obstructive pulmonary disease (COPD) (HR 2.52; 95% CI 1.09-5.83, p-value=0.031) or proxy of cardiovascular disease (HR 4.93; 95% CI 1.45-16.75, p-value=0.010), and presence of active cancer (HR 3.64; 95% CI 1.50-8.84, p-value=0.004), but not pneumonia severity.
conclusionsOne-year post-discharge mortality depends on underlying patients' comorbidities rather than COVID-19 pneumonia severity per se. Awareness among physicians of predictors of post-discharge mortality might be helpful in structuring a follow-up program for discharged patients.
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