Evidence map›Paper›PMID 36473203›Full record

ArticleAIDS care2023

Feasibility and preliminary effectiveness of integrating HIV prevention into an adolescent empowerment and livelihood intervention at youth clubs in rural Uganda.

Canice Christian, Jane Kabami, Dalsone Kwarisiima, Blian Beinamatsiko, Hellen Nakato, James Ward Khakshi, Munshi Sulaiman, Annah Komugisha, Harsha Thirumurthy, Diane V Havlir and 2 more

Open access · hybridAbstract read
In one paragraph

Article in AIDS care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Observational
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Canice ChristianDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-2502-8718
Jane KabamiInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0002-0265-3174
Dalsone KwarisiimaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0003-2886-9261
Blian BeinamatsikoInfectious Diseases Research Collaboration, Kampala, Uganda.
Hellen NakatoInfectious Diseases Research Collaboration, Kampala, Uganda.
James Ward KhakshiBRAC International, Kampala, Uganda.
Munshi SulaimanBRAC International, Kampala, Uganda.
Annah KomugishaBRAC International, Kampala, Uganda.
Harsha ThirumurthyPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-3308-7603
Diane V HavlirDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-0761-3136
Moses R KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0001-9106-4234
Gabriel ChamieDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-5860-8081
Infectious Diseases Research Collaboration · UGUniversity of California, San Francisco · USUniversity of Pennsylvania · US

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
NIAID NIH HHS UM1 AI068634NIAID NIH HHS UM1 AI068636
6 · The paper itself

Abstract

The uptake of HIV prevention services is lower among youth than adults in sub-Saharan Africa. Existing youth livelihood trainings offer a potential entry point to HIV prevention services. We determined feasibility and preliminary effectiveness of integrating HIV prevention into youth clubs implementing an empowerment and livelihood for adolescents (ELA) intervention in rural Uganda. Staff conducted community mobilization for youth (15-24 years) over one month. Clubs met (3×/week) over six months, with local peer mentors trained to teach life-skills and sexual/reproductive health education. We integrated mentor-led education on HIV prevention, including pre- and post-exposure prophylaxis (PrEP/PEP). Clubs offered on-site HIV testing, a field trip to a local clinic and PrEP referrals after one month and six months. Surveys were conducted at baseline and six months. Forty-two participants (24 adolescent girls/young women (AGYW) and 18 adolescent boys/young men (ABYM)) joined the clubs. At baseline, no participants accepted referral for PrEP, whereas 5/18 (28%) sexually active, HIV-negative AGYW requested PrEP referral at follow-up. One ABYM requested PEP referral. Integration of HIV prevention services into an established ELA curriculum at mentor-led youth clubs in rural Uganda was feasible. PrEP uptake increased among sexually active AGYW. Evaluation of this approach for HIV prevention among youth merits further study.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentAdultFeasibility StudiesFemaleHumansMaleMenUgandaAnti-HIV AgentsEast AfricaHIV preventionpost-exposure prophylaxis (PEP)Pre-exposure prophylaxis (PrEP)youth

Identifiers

PMID36473203
PMCPMC10006396
OpenAlexW4311660511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.