Evidence map›Paper›PMID 36473132›Full record

ArticleJCO oncology practice2023

Impact of a Hospital-Based Specialty Pharmacy in Partnership With a Care Coordination Organization on Time to Delivery and Receipt of Oral Anticancer Drugs.

Melissa P Beauchemin, Morgan R L Lichtenstein, Rohit Raghunathan, Sahil D Doshi, Shing Lee, Cynthia Law, Melissa K Accordino, Elena B Elkin, Jason D Wright, Dawn L Hershman

Open access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Melissa P BeaucheminSchool of Nursing, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-4058-1586
Morgan R L LichtensteinDivision of Hematology/Oncology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-2159-0065
Rohit RaghunathanHerbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
Sahil D DoshiDivision of Hematology/Oncology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Shing LeeDepartment of Biostatistics, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-8413-6869
Cynthia LawDivision of Hematology/Oncology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Melissa K AccordinoHerbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
Elena B ElkinDepartment of Health Policy and Management, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-8833-4213
Jason D WrightHerbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-6390-825X
Dawn L HershmanHerbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-8807-153X
Columbia University Irving Medical Center · US

Funding

Training Program in Cancer-related Population SciencesT32CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I., TERRY, MARY BETH · 2017 to 2021
$1.1M
Delays in Acquisition of Oral Antineoplastic AgentsR21CA242044 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERSHMAN, DAWN · 2020 to 2021
$417k
NCI NIH HHS R21 CA242044NCI NIH HHS T32 CA094061
6 · The paper itself

Abstract

purposeOral anticancer drug (OACD) prescriptions require extensive coordination between providers and payers, which can delay drug receipt. Specialty pharmacies facilitate communication between multiple entities. In 2018, our cancer center partnered with a freestanding organization to implement a hospital-based specialty pharmacy (HB-SP). We evaluated the time to drug receipt (TTR) before and after HB-SP implementation.

methodsData were prospectively collected on all new OACD prescriptions for adult oncology patients from January 1, 2018, to December 31, 2019. In fall 2018, a HB-SP was initiated. We collected patient sociodemographic, clinical, and prescription data. TTR was the number of days from OACD prescription to drug receipt. We used multivariable logistic regression to examine factors associated with TTR ≤ 7 days before and after HB-SP implementation.

resultsIn total, 954 patients were included, representing 1,102 new OACDs. The majority of prescribed drugs were targeted OACDs (56%, n = 617), and 71% (n = 779) required prior authorization. Of all prescriptions, 84% (n = 960) were successfully received with an overall median TTR of 7 days. In unadjusted analysis, HB-SP implementation, drug class, race and ethnicity, and prior authorization requirement were significantly associated with TTR. Adjusted analyses found that patients were more likely to receive their drugs ≤ 7 days after HB-SP implementation (53%

conclusionThe implementation of a HB-SP in partnership with a collaborative care model contributed to a decrease in TTR for OACDs. This difference is in part attributable to improved care coordination and communication. A centralized approach may improve overall efficiency due to fewer practice disruptions.

Indexed as

Antineoplastic AgentsNeoplasmsPharmacyAdultHospitalsHumansAntineoplastic Agents

Identifiers

PMID36473132
PMCPMC10022875
OpenAlexW4311658414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.