Evidence map›Paper›PMID 36473131›Full record

ArticleOncotarget2022

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD).

Mamoun Younes, Lin Zhang, Baharan Fekry, Kristin Eckel-Mahan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Obesity under the moonlight of c-MYC.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mamoun YounesDepartment of Pathology, George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA.
Lin ZhangDepartments of Pathology and Laboratory Medicine, McGovern Medical School at the University of Texas Health Science Center (UTHealth), Houston, TX 77225, USA.
Baharan FekryInstitute of Molecular Medicine, McGovern Medical School at the University of Texas Health Science Center (UTHealth), Houston, TX 77225, USA.
Kristin Eckel-MahanInstitute of Molecular Medicine, McGovern Medical School at the University of Texas Health Science Center (UTHealth), Houston, TX 77225, USA.
The University of Texas Health Science Center at Houston · USGeorge Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the expression of two hepatocyte nuclear factor 4 alpha (HNF4α) isoforms, p-STAT3. and c-Myc in 49 consecutive liver biopsies with nonalcoholic fatty liver disease (NAFLD) using immunohistochemistry. All 49 biopsies (100%) were positive for nuclear expression of P1-HNF4α. Twenty-eight (57%) cases were positive for P2-HNF4α, 6 (12%) were positive for p-STAT3 and 5 (10%) were positive for c-Myc. All 6 (100%) p-STAT3-positive cases were also positive for P2-HNF4α (

Indexed as

HypertensionNon-alcoholic Fatty Liver DiseaseFibrosisHumansSTAT3 Transcription FactorSTAT3 protein, humanSTAT3 Transcription Factorhepatocellular carcinomahepatocyte nuclear factor four alphaimmunohistochemistryisoformsteatohepatitis

Identifiers

PMID36473131
PMCPMC9726203
OpenAlexW4311579282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.