ArticleDiabetes care2023
Gestational Glucose Intolerance and Risk of Future Diabetes.
Article in Diabetes care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Association of maternal blood metabolomics and gestational diabetes mellitus risk: a systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2025Pooled it
- Polyendocrine Metabolic Ovarian Syndrome and the Entire Spectrum of Gestational Dysglycemia: A Population-Based Cohort Study.Diabetes, obesity & metabolism · 2026Article
- Article
- Gestational Glucose Intolerance and the Risk of Hypertensive Disorders of Pregnancy.Journal of the American Heart Association · 2026Article
- Associations between hematologic dynamics during pregnancy and obstetric complications: A retrospective observational study.PLoS medicine · 2026Observational
- Machine Learning-Derived Predictive Risk Score for Prediabetes and Type 2 Diabetes Development in Parous Women.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Serum microRNA-126 Levels Are Associated With Diabetic Nephropathy in Patients With Type 2 Diabetes Mellitus.International journal of endocrinology · 2026Article
- Gestational Glucose Intolerance and Risk of Obesity in Childhood and Adolescence.The Journal of clinical endocrinology and metabolism · 2025Article
- Resident and Physician Assistant Co-management-One Model for Reducing Inequities in Care for Patients with Diabetes.Journal of general internal medicine · 2025Article
- Gestational diabetes and parental type 2 diabetes as risk indicators for type 1 diabetes in offspring: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Review
- Postnatal Cardiometabolic Health After Metformin Use in Gestational Diabetes: A Secondary Analysis of the EMERGE Trial.The Journal of clinical endocrinology and metabolism · 2025Article
- Article
- Rationale and protocol for the Time to Move Randomized Crossover Trial: morning versus evening time physical activity and CGM-assessed glucose levels in individuals with pregnancy hyperglycemia.Frontiers in clinical diabetes and healthcare · 2025Article
- The simultaneous occurrence of gestational diabetes and hypertensive disorders of pregnancy affects fetal growth and neonatal morbidity.American journal of obstetrics and gynecology · 2024Article
- Risk of Neonatal Hypoglycemia in Infants of Mothers With Gestational Glucose Intolerance.Diabetes care · 2024Article
- Are miR-26a and miR-26b microRNAs potent prognostic markers of gestational diabetes?Health science reports · 2024Article
- Gestational glucose intolerance among pregnant women at the Cape Coast Teaching Hospital.BMC pregnancy and childbirth · 2024Article
- Article
- Understanding the role of childhood nurture, abuse, and stability on gestational diabetes in the Coronary Artery Risk Development in Young Adults study (CARDIA).Annals of epidemiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectivePregnant individuals are universally screened for gestational diabetes mellitus (GDM). Gestational glucose intolerance (GGI) (an abnormal initial GDM screening test without a GDM diagnosis) is not a recognized diabetes risk factor. We tested for an association between GGI and diabetes after pregnancy. RESEARCH DESIGN AND
methodsWe conducted a retrospective cohort study of individuals followed for prenatal and primary care. We defined GGI as an abnormal screening glucose-loading test result at ≥24 weeks' gestation with an oral glucose tolerance test (OGTT) that did not meet GDM criteria. The primary outcome was incident diabetes. We used Cox proportional hazards models with time-varying exposures and covariates to compare incident diabetes risk in individuals with GGI and normal glucose tolerance.
resultsAmong 16,836 individuals, there were 20,359 pregnancies with normal glucose tolerance, 2,943 with GGI, and 909 with GDM. Over a median of 8.4 years of follow-up, 428 individuals developed diabetes. Individuals with GGI had increased diabetes risk compared to those with normal glucose tolerance in pregnancy (adjusted hazard ratio [aHR] 2.01 [95% CI 1.54-2.62], P < 0.001). Diabetes risk increased with the number of abnormal OGTT values (zero, aHR 1.54 [1.09-2.16], P = 0.01; one, aHR 2.97 [2.07-4.27], P < 0.001; GDM, aHR 8.26 [6.49-10.51], P < 0.001 for each compared with normal glucose tolerance). The fraction of cases of diabetes 10 years after delivery attributable to GGI and GDM was 8.5% and 28.1%, respectively.
conclusionsGGI confers an increased risk of future diabetes. Routinely available clinical data identify an unrecognized group who may benefit from enhanced diabetes screening and prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.