Evidence map›Paper›PMID 36472772›Full record

ArticleAMB Express2022

Enzyme-treated chicory for cosmetics: application assessment and techno-economic analysis.

Suvi Tuulikki Häkkinen, Katarina Cankar, Liisa Nohynek, Marjut Suomalainen, Jeroen van Arkel, Matti Siika-Aho, Anna Twarogowska, Bart Van Droogenbroeck, Kirsi-Marja Oksman-Caldentey

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Suvi Tuulikki HäkkinenVTT Technical Research Centre of Finland Ltd, Tietotie 2, 02044, Espoo, Finland. suvi.hakkinen@vtt.fi.ORCID http://orcid.org/0000-0001-6959-3148
Katarina CankarWageningen Plant Research, Wageningen University & Research, Wageningen, The Netherlands.
Liisa NohynekVTT Technical Research Centre of Finland Ltd, Tietotie 2, 02044, Espoo, Finland.
Marjut SuomalainenVTT Technical Research Centre of Finland Ltd, Tietotie 2, 02044, Espoo, Finland.
Jeroen van ArkelWageningen Plant Research, Wageningen University & Research, Wageningen, The Netherlands.
Matti Siika-AhoVTT Technical Research Centre of Finland Ltd, Tietotie 2, 02044, Espoo, Finland.
Anna TwarogowskaILVO Institute for Agriculture, Fisheries and Food Research, Melle, Belgium.
Bart Van DroogenbroeckILVO Institute for Agriculture, Fisheries and Food Research, Melle, Belgium.
Kirsi-Marja Oksman-CaldenteyVTT Technical Research Centre of Finland Ltd, Tietotie 2, 02044, Espoo, Finland.
Tieto (Finland) · FIWageningen University & Research · NL

Funding

Horizon 2020 Framework Programme 652615
6 · The paper itself

Abstract

Chicory (Cichorium intybus L.) is an important industrial crop that produces large quantities of the dietary fiber inulin in its roots. Following inulin extraction, the bagasse is typically used as animal feed, but it contains numerous bioactive secondary metabolites with potential applications in healthcare and cosmetic products. Here we assessed the antimicrobial properties of chicory biomass pre-treated with various enzymes alone and in combination to release the bioactive compounds and increase their bioavailability. We found that pre-treatment significantly increased the antimicrobial activity of this industrial by-product, yielding an extract that inhibited typical skin pathogens in a cosmetic formula challenge test. We also evaluated the valorization of chicory biomass as a bioactive cosmetic ingredient. Economic feasibility was estimated by combining our experimental results with a conceptual techno-economic analysis. Our results suggest that chicory biomass can be utilized for the sustainable production of efficacious cosmetic ingredients.

Indexed as

Antimicrobial activityBy-productChicoryEnzyme treatmentTechno-economic analysis

Identifiers

PMID36472772
PMCPMC9727056
OpenAlexW4310947229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.