ArticleEuropean radiology2023
Value of CEUS combined with feeding artery ablation in the microwave ablation of large solid benign thyroid nodules.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- The efficacy and safety of microwave ablation in benign large thyroid nodules (≥4 cm).European thyroid journal · 2026Article
- Application of contrast-enhanced ultrasound to improve the management of microwave thyroid nodule ablation.Ultrasound (Leeds, England) · 2026Review
- Evaluating microwave ablation for treating large benign thyroid nodules.Gland surgery · 2026Article
- The occurrence of hyperthyroidism after thermal ablation for thyroid papillary carcinoma: a retrospective multicentre observational study.BMC cancer · 2025Observational
- Review
- Letter to the Editor: "Efficacy of single‑session radiofrequency ablation (RFA) in rendering euthyroidism for persistent/relapsed Graves' disease, a pilot study".European radiology · 2025Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo investigate the value of contrast-enhanced ultrasound (CEUS) combined with feeding artery ablation in the microwave ablation (MWA) of large solid benign thyroid nodules (LSBTNs) with a diameter ≥ 4 cm.
methodsWe retrospectively analyzed 122 patients with LSBTN ≥ 4 cm in diameter treated with MWA. During evaluations before and after MWA, 53 patients who underwent conventional ultrasound examination were classified as the routine group, and 69 patients who underwent CEUS combined with feeding artery ablation were classified as the union group. The differences in ablation energy required per milliliter (AERPM), complication rate, regrowth rate, and volume reduction rate (VRR) were compared between the two groups.
resultsThe AERPM of the union group was significantly less than that of the routine group (956.3 ± 38.5 J/mL vs. 1025.9 ± 121.5 J/mL, p < 0.001). The complication rate of the routine group was significantly higher than that of the union group (13.2% vs. 2.9%, p = 0.031). The regrowth rate of the routine group (22.6%, 12/53) was significantly higher than that of the union group (7.2%, 5/69) (p = 0.015). At the 1st, 3rd, 6th, 12th, 18th, and 24th month after ablation, the mean VRRs of the routine group were significantly less than those of the union group, with p values of < 0.001, < 0.001, 0.002, 0.007, 0.013, and < 0.001, respectively.
conclusionsThe application of CEUS combined with feeding artery ablation in the MWA of LSBTNs is helpful to reduce the regrowth rate, improve the ablation efficiency, and reduce bleeding. KEY POINTS: • CEUS combined with feeding artery ablation in MWA of LSBTNs is helpful to reduce regrowth rate. • CEUS combined with feeding artery ablation can help improve ablation efficiency than conventional ultrasound in LSBTNs. • CEUS combined with feeding artery ablation helps reduce the incidence of bleeding during MWA.
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