ArticleEuropean radiology2023
WHO/ISUP grade and pathological T stage of clear cell renal cell carcinoma: value of ZOOMit diffusion kurtosis imaging and chemical exchange saturation transfer imaging.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Navigating the diagnostic 'gray zone': prospective evaluation of an integrated MRI-Biomarker model for renal allograft triage.Annals of medicine · 2026Article
- Quantitative MRI for World Health Organisation/International Society of Urological Pathology Grading of Renal Cell Carcinoma: a systematic review and diagnostic meta-analysis.European radiology · 2026Article
- An interpretable machine learning model based on habitat radiomics combined with deep learning for predicting the WHO/ISUP grade of patients with clear cell renal cell carcinoma.BMC medical imaging · 2026Article
- Chemical exchange saturation transfer magnetic resonance imaging of the kidney: applications and challenges.Abdominal radiology (New York) · 2025Review
- Evaluation of renal masses with CEST MRI: Protocol optimization and preliminary results.Magnetic resonance in medicine · 2025Article
- MRI-based diffusion weighted imaging and diffusion kurtosis imaging grading of clear cell renal cell carcinoma using a deep learning classifier.Oncology letters · 2025Article
- Computed tomography-based delta-radiomics analysis for preoperative prediction of ISUP pathological nuclear grading in clear cell renal cell carcinoma.Abdominal radiology (New York) · 2025Article
- Prognostic significance of systemic immunoinflammatory biomarkers in patients with clear cell renal cell carcinoma: a retrospective multicenter analysis.Frontiers in immunology · 2025Article
- Exploring the value of arterial spin labeling and six diffusion MRI models in differentiating solid benign and malignant renal tumors.European radiology experimental · 2024Article
- Feasibility and Reproducibility of T2 Mapping Compared with Diffusion-Weighted Imaging in Solid Renal Masses.Bioengineering (Basel, Switzerland) · 2024Article
- Synthesizing High b-Value Diffusion-Weighted Imaging of Gastric Cancer Using an Improved Vision Transformer CycleGAN.Bioengineering (Basel, Switzerland) · 2024Article
- Explore the Value of Multi-Parameter MRI in Non-Invasive Assessment of Prognostic Risk and Oxford Classification in Children with IgAN or IgAVN.Bioengineering (Basel, Switzerland) · 2024Article
- Article
- Amide Proton Transfer-Weighted Imaging Combined with ZOOMit Diffusion Kurtosis Imaging in Predicting Lymph Node Metastasis of Cervical Cancer.Bioengineering (Basel, Switzerland) · 2023Article
- Application of DKI and IVIM imaging in evaluating histologic grades and clinical stages of clear cell renal cell carcinoma.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the value of ZOOMit diffusion kurtosis imaging (DKI) and chemical exchange saturation transfer (CEST) imaging in predicting WHO/ISUP grade and pathological T stage in clear cell renal cell carcinoma (ccRCC).
methodsForty-six patients with ccRCC were included in this retrospective study. All participants underwent MRI including ZOOMit DKI and CEST. The non-Gaussian mean kurtosis (MK), mean diffusivity (MD), magnetization transfer ratio asymmetry (MTRasym (3.5 ppm)), and S
resultsThe ADC, MD, and S
conclusionThe microstructural and biochemical assessment of ZOOMit DKI and CEST allowed for the characterization of different WHO/ISUP grades and pT stages in ccRCC. MTRasym (3.5 ppm) combined with MD showed the best diagnostic performance for WHO/ISUP grading. KEY POINTS: • Both diffusion kurtosis imaging (DKI) and chemical exchange saturation transfer (CEST) can be used to predict the WHO/ISUP grade and pathological T stage. • MTRasym (3.5 ppm) combined with MD showed the highest AUC (0.930; 95% CI, 0.858-1.000) in WHO/ISUP grading. • MTRasym at 3.5 ppm showed a positive correlation with mean kurtosis.
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