Evidence map›Paper›PMID 36472629›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2023

Anticancer and chemosensitizing activities of stilbenoids from three orchid species.

Khin Lay Sein, Nonthalert Lertnitikul, Rutt Suttisri, Suree Jianmongkol

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Antitumor Activity of Isalpinin fromMolecules (Basel, Switzerland) · 2025
    Article
  5. Phytochemical Analysis ofPlants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Khin Lay SeinDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Nonthalert LertnitikulDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Rutt SuttisriDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Suree JianmongkolDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand. suree.j@pharm.chula.ac.th.ORCID https://orcid.org/0000-0002-2919-2339
Chulalongkorn University · TH

Funding

Chulalongkorn University the graduate scholarship for ASEAN and Non-ASEAN countries to KL SeinThailand Science Research and Innovation (TSRI), Thailand Fundamental Fund No. CUFRB65 hea(53)-062-33-06
6 · The paper itself

Abstract

Recently, we have isolated and identified several bioactive flavonoids and stilbenoids with potential anticancer activity from Thai orchids. In this study, we further investigated the cytotoxic and chemosensitizing activities of these phytochemicals (namely, pinocembrin, cardamonin, isalpinin, galangin, pinosylvin monomethyl ether, 2,3'-dihydroxy-5'-methoxystilbene, (E)-2,5'-dihydroxy-2'-(4-hydroxybenzyl)-3'-methoxystilbene, 2,3-dihydroxy-3',5'-dimethoxystilbene, 2,3'-dihydroxy-5,5'-dimethoxystilbene, 3,4'-dihydroxy-5-methoxystilbene and batatasin III) against breast cancer MCF7 cells and its two multidrug resistant (MDR) sublines (MCF7/DOX and MCF7/MX). Cytotoxicity was determined with MTT assay for the estimation of the half maximal cytotoxic concentrations (IC

Indexed as

Antineoplastic AgentsBreast NeoplasmsStilbenesATP-Binding Cassette, Sub-Family C ProteinsDoxorubicinDrug Resistance, MultipleDrug Resistance, NeoplasmEthersFemaleHumansPhytoalexinsAntineoplastic AgentsATP-Binding Cassette, Sub-Family C ProteinsDoxorubicinEthersPhytoalexinspinosylvinStilbenesBreast cancer cellsChemosensitizing effectDrug efflux transportersDrug synergismPinosylvin monomethyl ether

Identifiers

PMID36472629
OpenAlexW4310775667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.