Evidence map›Paper›PMID 36472543›Full record

Trial reportDiabetes technology & therapeutics2023

Improved Glycemia with Hybrid Closed-Loop Versus Continuous Subcutaneous Insulin Infusion Therapy: Results from a Randomized Controlled Trial.

Satish K Garg, George Grunberger, Ruth Weinstock, Margaret L Lawson, Irl B Hirsch, Linda A DiMeglio, Rodica Pop-Busui, Athena Philis-Tsimikas, Mark Kipnes, David R Liljenquist and 21 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes technology & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Effect of Automated Insulin Delivery System Therapy at Diagnosis on Metabolic Control in Children and Adolescents with Type 1 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  12. Article
  13. Early Stages of Automated Insulin Delivery.Journal of diabetes science and technology · 2025
    Review
  14. Early Stages of Automated Insulin Delivery.Diabetes technology & therapeutics · 2025
    Review
  15. Registration and Real-Life Studies on Automated Insulin Delivery Systems.Journal of diabetes science and technology · 2025
    Review
  16. Review
  17. Article
  18. Continuous Glucose Monitoring Attrition in Youth With Type 1 Diabetes.The science of diabetes self-management and care · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 2 countries.

Satish K GargBarbara Davis Center for Diabetes, Aurora, Colorado, USA.
George GrunbergerGrunberger Diabetes Institute, Bloomfield Hills, Michigan, USA.
Ruth WeinstockUpstate Medical University, Syracuse, New York, USA.ORCID 0000-0001-5859-5666
Margaret L LawsonChildren's Hospital of Eastern Ontario, Ottawa, Ontario, CAN.
Irl B HirschUniversity of Washington, Seattle, Washington, USA.ORCID 0000-0003-1675-8417
Linda A DiMeglioIndiana University-Riley Hospital for Children, Indianapolis, Indiana, USA.
Rodica Pop-BusuiUniversity of Michigan Health System-University Hospital, Ann Arbor, Michigan, USA.
Athena Philis-TsimikasScripps Whittier Diabetes Institute, La Jolla, California, USA.
Mark KipnesDiabetes and Glandular Disease Clinic, San Antonio, Texas, USA.
David R LiljenquistRocky Mountain Diabetes and Osteoporosis Center, Idaho Falls, Idaho, USA.
Ronald L BrazgRainier Clinical Research Center, Renton, Washington, USA.
Yogish C KudvaMayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-0285-6622
Bruce A BuckinghamStanford University School of Medicine, Stanford, California, USA.
Janet B McGillWashington University in Saint Louis, St. Louis, Missouri, USA.ORCID 0000-0002-6228-6521
Anders L CarlsonPark Nicollet International Diabetes Center, Minneapolis, Minnesota, USA.
Amy B CriegoPark Nicollet International Diabetes Center, Minneapolis, Minnesota, USA.
Mark P ChristiansenDiablo Clinical Research, Walnut Creek, California, USA.
Kevin B KaisermanSoCal Diabetes, Torrance, California, USA.
Kurt J GriffinUniversity of South Dakota-Sanford Research, Sioux Falls, South Dakota, USA.
Greg P ForlenzaBarbara Davis Center for Childhood Diabetes, Aurora, Colorado, USA.ORCID 0000-0003-3607-9788
Bruce W BodeAtlanta Diabetes Associates, Atlanta, Georgia, USA.
Robert H SloverBarbara Davis Center for Childhood Diabetes, Aurora, Colorado, USA.
Ashleigh KeiterMedtronic, Northridge, California, USA.
Chenxiao LingMedtronic, Northridge, California, USA.
Briggitte MarinosMedtronic, Northridge, California, USA.
Toni L CorderoMedtronic, Northridge, California, USA.ORCID 0000-0003-4597-4194
John ShinMedtronic, Northridge, California, USA.
Scott W LeeMedtronic, Northridge, California, USA.
Andrew S RhinehartMedtronic, Northridge, California, USA.
Robert A VigerskyMedtronic, Northridge, California, USA.ORCID 0000-0002-3546-3385
Adult and Pediatric MiniMed™ HCL Outcomes 6-month RCT: HCL versus CSII Control Study Group
Medtronic (United States) · USPark Nicollet Clinic · USAmerican Youth Soccer Organization · USAtlanta Diabetes Associates · USChildren's Hospital of Eastern Ontario · CADiabetes & Glandular Disease Clinic · USDiablo Clinical Research · USGrunberger Diabetes Institute · USMayo Clinic · USRainier Clinical Research Center · USRiley Hospital for Children · USRocky Mountain Diabetes and Osteoporosis Center · USScripps Whittier Diabetes Institute · USStanford University · USSUNY Upstate Medical University · USUniversity of Colorado Health · USUniversity of Michigan · USUniversity of South Dakota · USUniversity of Washington · USWashington University in St. Louis · US

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
NIDDK Diabetic Foot Consortium Clinical Research UnitU01DK119083 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RODICA BUSUI (POP-BUSUI), Crystal Murray Holmes · 2018 to 2026
$5.5M
Modeling and modulating insulin delivery in automated insulin delivery systems to accommodate for meal compositionsK23DK121942 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EKHLASPOUR, LAYA · 2020 to 2024
$964k
NIDDK NIH HHS K23 DK121942NIDDK NIH HHS P30 DK111022NIDDK NIH HHS U01 DK119083
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1Diabetic KetoacidosisAdolescentAdultAgedAged, 80 and overBlood GlucoseBlood Glucose Self-MonitoringChildChild, PreschoolGlycated HemoglobinHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsMiddle AgedBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinA1CAdultDiabetes treatment satisfactionHybrid closed loopPediatricTime below rangeTime in rangeType 1 diabetes

Identifiers

PMID36472543
PMCPMC10081723
OpenAlexW4310772909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.