Evidence map›Paper›PMID 36472445›Full record

ArticlemSphere2022

Coexistence of Multidrug Resistance and Virulence in a Single Conjugative Plasmid from a Hypervirulent Klebsiella pneumoniae Isolate of Sequence Type 25.

Peiwen Xia, Miao Yi, Yaling Yuan, Jinzhu Huang, Bingxue Yang, Jiajia Liao, Zijun Dang, Shengli Luo, Yun Xia

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Antimicrobial resistance dynamics inBiochemistry and biophysics reports · 2026
    Article
  6. Article
  7. An ISFrontiers in microbiology · 2026
    Article
  8. Divergent Virulence Traits inInfection and drug resistance · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. HypervirulentInfection and drug resistance · 2023
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Peiwen XiaDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Miao YiDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yaling YuanDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jinzhu HuangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Bingxue YangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiajia LiaoDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zijun DangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shengli LuoDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yun XiaDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-3136-8548
The Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) has received considerable attention. Typically, the genetic elements that confer virulence are harbored by nonconjugative plasmids. In this study, we report a CR-hvKP strain, CY814036, of high-risk sequence type 25 (ST25) and the K2 serotype, which is uncommon among K. pneumoniae isolates but caused serious lung infection in a tertiary teaching hospital in China. Whole-genome sequencing (WGS) revealed a rare conjugative plasmid, pCY814036-iucA, carrying a virulence-associated

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesCarbapenemsDrug Resistance, MultipleHumansPlasmidsVirulenceAnti-Bacterial Agentsbeta-LactamasesCarbapenemsblaKPC-2conjugativecotransmissioniuc operonKlebsiella pneumoniaeST25

Identifiers

PMID36472445
PMCPMC9769751
OpenAlexW4310788023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.