Evidence map›Paper›PMID 36472436›Full record

ArticleJournal of bacteriology2023

Small RNAs Activate Salmonella Pathogenicity Island 1 by Modulating mRNA Stability through the

Sabrina Z Abdulla, Kyungsub Kim, Muhammad S Azam, Yekaterina A Golubeva, Fatih Cakar, James M Slauch, Carin K Vanderpool

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Molecular strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. TheJournal of bacteriology · 2025
    Article
  11. Advances in sRNA-mediated regulation ofFrontiers in cellular and infection microbiology · 2025
    Review
  12. Article
  13. OFrontiers in cellular and infection microbiology · 2025
    Article
  14. ThebioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Improved RNA stability estimation through Bayesian modeling reveals mostProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sabrina Z AbdullaDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Kyungsub KimDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Muhammad S AzamDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Yekaterina A GolubevaDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Fatih CakarDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
James M SlauchDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0003-4634-9702
Carin K VanderpoolDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
University of Illinois Urbana-Champaign · US

Funding

Small RNA Regulation in BacteriaR35GM139557 · NIGMS · UNIVERSITY OF MINNESOTA · PI Carin K Vanderpool · 2021 to 2026
$2.6M
Integration of Small RNAs in Control of Salmonella Pathogenicity Island 1R01GM120182 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SLAUCH, JAMES M., VANDERPOOL, CARIN K · 2016 to 2019
$1.2M
Regulation of the Salmonella Pathogenicity Island 1 Type III Secretion System via the hilD 3' untranslated regionR21AI166495 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SLAUCH, JAMES M. · 2022 to 2023
$413k
NIAID NIH HHS R21 AI166495NIGMS NIH HHS R01 GM120182NIGMS NIH HHS R35 GM139557
6 · The paper itself

Abstract

Salmonella enterica serovar Typhimurium is an enteric pathogen associated with foodborne disease. Salmonella invades the intestinal epithelium using a type three secretion system encoded on Salmonella pathogenicity island 1 (SPI-1). SPI-1 genes are tightly regulated by a complex feed-forward loop to ensure proper spatial and temporal expression. Most regulatory input is integrated at HilD, through control of

Indexed as

RNA, Small UntranslatedTranscription Factors3' Untranslated RegionsAnimalsBacterial ProteinsGene Expression Regulation, BacterialGenomic IslandsMiceRNA, MessengerRNA StabilitySalmonella typhimurium3' Untranslated RegionsBacterial ProteinsRNA, MessengerRNA, Small UntranslatedTranscription FactorsHfqRNase ESdsRSpot 42

Identifiers

PMID36472436
PMCPMC9879128
OpenAlexW4310872288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.