ArticleBMC psychiatry2022
Adherence to prescribed antihypertensive medication among patients with depression in the United States.
Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adherence to antihypertensives in the United States: A comparative meta-analysis of 23 million patients.Journal of clinical hypertension (Greenwich, Conn.) · 2024Pooled it
- Clinical Decision Support and Cardiometabolic Medication Adherence: A Randomized Clinical Trial.JAMA network open · 2025 · on this mapTrial
- Prevalence of adherence to antihypertensive treatment: a comparison of drug biochemical analysis and the self-report scale.Clinical hypertension · 2026Article
- Psychosocial predictors of non-adherence to antihypertensive medication among Korean adults: A nationwide cross-sectional study.PloS one · 2026Article
- Latent Class Analysis of Medication Adherence and Its Influencing Factors Among Rural Hypertensive Patients in Shanxi Province, China.Patient preference and adherence · 2026Article
- Development Track of Compliance With Dual Antiplatelet Therapy and Analysis of Potential Categories in Patients With ACS After PCI.Reviews in cardiovascular medicine · 2025Article
- Depression as a mediator between socioeconomic status and risk of All-Cause and cardiovascular mortality in diabetes and prediabetes.Scientific reports · 2025Article
- Self-Efficacy, Social Support, and Depression: Mediators of Medication Adherence in Dialysis Patients.Healthcare (Basel, Switzerland) · 2025Article
- Socioeconomic Factors Associated with Non-Adherence to Antihypertensive Treatment Among Older Adults Affiliated to the "Pension 65" Program in Peru.Patient preference and adherence · 2025Article
- Modifiable Risk Factors Associated With Cognitive Decline in Late Life Depression: Findings From the Canadian Longitudinal Study on Aging: Facteurs de risque modifiables associés au déclin cognitif dans la dépression en fin de vie : constatations de l'Étude longitudinale canadienne sur le vieillissement.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2024Article
- Associations between Life's Essential 8 and abdominal aortic calcification among US Adults: a cross-sectional study.BMC public health · 2024Article
- Associations of the Charlson comorbidity index with depression and mortality among the U.S. adults.Frontiers in public health · 2024Article
- Tuberculosis survivors and the risk of cardiovascular disease: analysis using a nationwide survey in Korea.Frontiers in cardiovascular medicine · 2024Article
- Unveiling the Nexus: Depressive Symptoms and Medication Adherence in Hypertensive Patients' Self-care: A Systematic Review.Materia socio-medica · 2024Review
- Self-Reported Medication Adherence Among Older People Admitted to Hospital: A Descriptive Study.Drugs - real world outcomes · 2023Article
- Association of Depression with Long-Term Cardiovascular Risks in Older Patients with Obstructive Sleep Apnea.Nature and science of sleep · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertensive patients with depression have a higher mortality rate and a worse prognosis compared with hypertensive only. Depression may reduce medication adherence in hypertension patients.
methodsThis study includes respondents in the National Health and Nutritional Examination Survey (NHANES) database from 2005 to 2018 who had previously been diagnosed with hypertension. Medication adherence was defined as taking medication as recommended by a physician. The depressive state was assessed using the patient health questionnaire (PHQ)-9.
resultsNine thousand one hundred eighty-six respondents were included in the analysis. Medication adherence was associated with depression (odds ratio [OR]: 1.48, 95% confidence interval [CI]: 1.26 to1.75) and depression score (OR: 1.04 per each point increase, 1.03 to 1.05) in the unadjusted analyses. After adjusting for clinical and socioeconomic/demographic factors, there were significant statistical correlations between depression score and medication adherence (aOR: 1.02 per each point increase, 1.00 to 1.03, p < 0.05), but there was no significant statistical correlation between depression and medication adherence (p > 0.05). It was still statistically significant relationships between sex, age, body mass index (BMI), race, marital status, and health insurance with medication adherence after adjusted socioeconomic/demographic factors.
conclusionDepression was marginally associated with poor medication adherence in hypertensive patients, and the correlation increased with depression degree. Moreover, socioeconomic/demographic factors have an independent impact on medication adherence including sex, age, BMI, race, marital status, and health insurance.
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