ArticleBMC infectious diseases2022
Risk factors of reinfection after prosthesis removal and antibiotic bone cement spacer implantation for the treatment of periprosthetic joint infection.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Risk factors predicting the reinfection in periprosthetic joint infection with sinus tracts following prosthesis removal and antibiotic bone cement spacer implantation: a case control study.BMC infectious diseases · 2025Article
- Predictive Factors for Risk of Reinfection in Septic Two-Stage Revision of Total Hip and Knee Arthroplasties.Antibiotics (Basel, Switzerland) · 2025Article
- Value of inflammation and nutrition markers in predicting the failure of prosthesis removal and antibiotic bone cement spacer implantation for PJI treatment.Frontiers in cellular and infection microbiology · 2025Article
- Article
- The presence of a sinus tract is associated with reinfection after two-stage revision surgery for prosthetic hip joint infection: a case-control study.BMC musculoskeletal disorders · 2024Article
- Changes in serum inflammatory factors after hip arthroplasty and analysis of risk factors for prosthesis loosening.American journal of translational research · 2024Article
- Two-stage revision in periprosthetic joint infection of the hip using a new intraoperatively molded articulating spacer design.Journal of clinical orthopaedics and trauma · 2023Article
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4 authors at 2 institutions in 1 country.
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Abstract
backgroundProsthesis removal and antibiotic bone cement spacer implantation is a very important link in two-stage revision of periprosthetic joint infection (PJI) after artificial joint replacement, which is key to the smooth progress of second-stage revision surgery. There are few reports on the risk factors of reinfection after prosthesis removal and antibiotic bone cement spacer implantation for PJI. This study aimed to investigate the risk factors of reinfection after prosthesis removal and antibiotic bone cement spacer implantation for the treatment of PJI.
methodsClinical data of 40 patients who underwent prosthesis removal and antibiotic bone cement spacer implantation for PJI after arthroplasty in our hospital from January 2013 to July 2019 were retrospectively analyzed. During the follow-up period of at least 2 years, 21 patients underwent complete two-stage revision after the removal of the antibiotic bone cement spacer, and 19 patients did not receive a new prosthesis due to other factors, such as reinfection or the patient's wishes, record the infection control of patients during the treatment. Reinfection after prosthesis removal and antibiotic bone cement spacer implantation was defined as failure of effective control of infection, symptoms of reinfection, requires increased antibiotic therapy or reoperation. Multivariate Cox proportional hazards model was used to analyze the risk factors associated with reinfection after prosthesis removal and antibiotic bone cement spacer implantation.
resultsOf the 40 patients, nine (22.5%) developed reinfection after prosthesis removal and antibiotic bone cement spacer implantation with a mean follow-up duration of 31 months, and multivariate analysis revealed that history of prior revision surgery (hazard ratio [HR] = 6.317, confidence interval [CI]: 1.495-26.700; p = 0.012) and presence of sinus tract before treatment (HR = 5.117, 95% CI: 1.199-21.828; p = 0.027) were independent risk factors for reinfection after prosthesis removal and antibiotic bone cement spacer implantation.
conclusionHistory of prior revision surgery and presence of sinus tract are two independent risk factors for reinfection in patients with PJI treated with prosthesis removal and antibiotic bone cement spacer implantation.
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