ArticleBMC neurology2022
3D slicer-based calculation of hematoma irregularity index for predicting hematoma expansion in intracerebral hemorrhage.
Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Research on predicting risk factors for re-bleeding in the acute phase of intracerebral hemorrhage using machine learning algorithms.Frontiers in medicine · 2026Article
- Empirical antibiotic therapy for spontaneous intracerebral hemorrhage-associated pneumonia: an ICU-based single-centered retrospective cohort study.BMC infectious diseases · 2025Article
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- Comparison of brainstem hematoma volume evaluation techniques with a novel quantitative approach.Neuroradiology · 2025Article
- PROMISE: Prognostic Radiomic Outcome Measurement in Acute Subdural Hematoma Evacuation Post-Craniotomy.Brain sciences · 2025Article
- Risk factors and preventive strategies for postoperative cerebral infarction in patients with hypertensive intracerebral hemorrhage.American journal of translational research · 2025Article
- Clinical and Imaging Predictors of Hematoma Expansion in Spontaneous Intracerebral Hemorrhage: Development of a Prognostic Model.Risk management and healthcare policy · 2025Article
- A correlation study between prostate necrosis rate calculated by 3D Slicer software and clinical efficacy of prostatic artery embolization, along with an analysis of predictors of clinical success after prostatic artery embolization.Abdominal radiology (New York) · 2024Article
- Exploring the Application of the Artificial-Intelligence-Integrated Platform 3D Slicer in Medical Imaging Education.Diagnostics (Basel, Switzerland) · 2024Review
- Percutaneous Endoscopic Transforaminal Discectomy for the Treatment of Lumbar Disc Herniation with Different Migration Levels: A Retrospective Study.Journal of pain research · 2024Article
- Changes in hematoma volume following aneurysmal subarachnoid hemorrhage and its impact on patient prognosis.Frontiers in neurology · 2024Article
- Predicting cerebral edema in patients with spontaneous intracerebral hemorrhage using machine learning.Frontiers in neurology · 2024Article
- How much is enough? Hematoma clearance thresholds and 30-day outcomes after sMIS for ICH across overall and baseline volume strata.Frontiers in neurologyArticle
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIrregular hematoma is considered as a risk sign of hematoma expansion. The aim of this study was to quantify hematoma irregularity with computed tomography based on 3D Slicer.
methodsPatients with spontaneous intracerebral hemorrhage who underwent an initial and subsequent non-contrast computed tomography (CT) at a single medical center between January 2019 to January 2020 were retrospectively identified. The Digital Imaging and Communication in Medicine (DICOM) standard images were loaded into the 3D Slicer, and the surface area (S) and volume (V) of hematoma were calculated. The hematoma irregularity index (HII) was defined as [Formula: see text]. Logistic regression analyses and receiver operating characteristic (ROC) curve analysis were performed to assess predictive performance of HII.
resultsThe enrolled patients were divided into those with hematoma enlargement (n = 36) and those without the enlargement (n = 57). HII in hematoma expansion group was 130.4 (125.1-140.0), and the index in non-enlarged hematoma group was 118.6 (113.5-122.3). There was significant difference in HII between the two groups (P < 0.01). Multivariate logistic regression analysis revealed that the HII was significantly associated with hematoma expansion before (odds ratio = 1.203, 95% confidence interval [CI], 1.115-1.298; P < 0.001) and after adjustment for age, hematoma volume, Glasgow Coma Scale score (odds ratio = 1.196, 95% CI, 1.102-1.298, P < 0.001). The area under the ROC curve was 0.86 (CI, 0.78-0.93, P < 0.01), and the best cutoff of HII for predicting hematoma growth was 123.8.
conclusionAs a quantitative indicator of irregular hematoma, HII can be calculated using the 3D Slicer. And the HII was independently correlated with hematoma expansion.
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