Evidence map›Paper›PMID 36471262›Full record

ArticleBMC pregnancy and childbirth2022

Clinical-epidemiological characteristics and maternal-foetal outcomes in pregnant women hospitalised with COVID-19 in Venezuela: a retrospective study.

Fhabián S Carrión-Nessi, Mercedes P Castro, Diana C Freitas-De Nobrega, Augusto Moncada-Ortega, Óscar D Omaña-Ávila, Daniela L Mendoza-Millán, María V Marcano-Rojas, Nayren J Trejo, Isabella V Virriel, Melynar Chavero and 3 more

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Current update on malaria in pregnancy: a systematic review.Tropical diseases, travel medicine and vaccines · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fhabián S Carrión-Nessi *Biomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela. fhabiancarrion@gmail.com.
Mercedes P Castro *Obstetrics and Gynaecology Department, San Cristobal Central Hospital, San Cristobal, Venezuela.
Diana C Freitas-De NobregaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Augusto Moncada-OrtegaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Óscar D Omaña-ÁvilaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Daniela L Mendoza-MillánBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
María V Marcano-RojasBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Nayren J Trejo"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Isabella V Virriel"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Melynar ChaveroBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Natasha A Camejo-ÁvilaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Alfonso J Rodriguez-MoralesGrupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de Las Américas - Institución Universitaria Visión de Las Américas, Pereira, Risaralda, Colombia.
David A Forero-PeñaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela. vacter.cv@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn low- and middle-income countries, pregnant women and newborns are more vulnerable to adverse outcomes from coronavirus disease 2019 (COVID-19). However, in Venezuela, there are no integrated data in a national surveillance system to identify the clinical-epidemiological characteristics and maternal-foetal outcomes of pregnant women hospitalised with COVID-19.

methodsA retrospective study was conducted among Venezuelan pregnant women hospitalised with COVID-19 seen at the "Ruiz y Páez" University Hospital Complex and the San Cristobal Central Hospital between June 2020 and September 2021. Information was obtained from physical and digitised clinical records using a purpose-designed proforma to collect epidemiological, clinical, paraclinical, treatment, obstetric and perinatal complications, and maternal-foetal outcomes data.

resultsA total of 80 pregnant women with confirmed severe acute respiratory syndrome coronavirus 2 infection were seen within the study period, 59 (73.8%) survived and 21 (26.2%) died. The median (interquartile range) age was 29 (23-33) years, the majority being in the third trimester of pregnancy (81.2%; n = 65). Interestingly, four (5%) pregnant women were co-infected with malaria by Plasmodium vivax and three (3.8%) with syphilis. The most frequent symptoms were fever (75%; n = 60), dry cough (68.8%; n = 55), dyspnoea (55%; n = 44), and headache (53.8%; n = 43). The most frequent maternal complications were anaemia (51.5%; n = 66) and hypertensive disorders of pregnancy (17.5%; n = 14). The most frequent perinatal complications were preterm delivery (39.2%; n = 20/51) and oligohydramnios (31.3%; n = 25). A total of 29 (36.3%) adverse foetal outcomes were documented, 21 stillbirth and eight abortions.

conclusionThis is the first study to describe the clinical-epidemiological behaviour of COVID-19 in hospitalised Venezuelan pregnant women. Anaemia, hypertensive disorders of pregnancy, oligohydramnios, and low birth weight were the most frequent maternal-foetal complications in this population of pregnant women.

Indexed as

AnemiaCOVID-19Hypertension, Pregnancy-InducedOligohydramniosPregnancy Complications, InfectiousPremature BirthAdultFemaleHumansInfant, NewbornPregnancyPregnancy OutcomePregnant PeopleRetrospective StudiesStillbirthVenezuelaCOVID-19EpidemiologyMaternal-foetal outcomePregnancyVenezuela

Identifiers

PMID36471262
PMCPMC9720989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.