Evidence map›Paper›PMID 36471059›Full record

Trial reportSurgical endoscopy2023

Colon capsule endoscopy following incomplete colonoscopy in routine clinical settings.

Anne-Line Volden Havshoi, Ulrik Deding, Sofie Sajan Jensen, Per Vadgaard Andersen, Lasse Kaalby, Issam Al-Najami

Registry-linked trialAbstract readClinical TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04307901 (Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04307901 recruitingnot on this map

Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy

TypeobservationalSponsorOdense University HospitalRan2020 to 2030Enrolled600ConditionsColorectal Cancer, Colorectal PolypArmsColon capsule endoscopy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anne-Line Volden HavshoiDepartment of Surgery, Odense University Hospital, Svendborg, Denmark.
Ulrik DedingDepartment of Surgery, Odense University Hospital, Svendborg, Denmark. ulrik.deding@rsyd.dk.ORCID 0000-0002-8263-2989
Sofie Sajan JensenDepartment of Surgery, Odense University Hospital, Svendborg, Denmark.
Per Vadgaard AndersenDepartment of Surgery, Odense University Hospital, Svendborg, Denmark.
Lasse KaalbyDepartment of Surgery, Odense University Hospital, Svendborg, Denmark.
Issam Al-NajamiDepartment of Surgery, Odense University Hospital, Svendborg, Denmark.
Odense University Hospital · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColon capsule endoscopy (CCE) was introduced in our department on two indications; following incomplete colonoscopy as an alternative to CT colonography, and in patients with a history of incomplete colonoscopy as an alternative to anesthesia-assisted (AA) colonoscopy. We aimed to compare the quality of CCE, defined by completion rate and polyp detection rate (PDR), with that of CT colonography and AA colonoscopy, respectively.

methodsPatients referred for CCE from May 2020 until November 2021 were consecutively included in this prospective cohort study. Demographics, indication and CCE outcomes were registered from the electronic patient record. Completion rate and PDR in CCE as an alternative to CT colonography were compared with those of a historical cohort undergoing CT colonography following incomplete colonoscopy. Completion rate and PDR in CCE as an alternative to AA colonoscopy were compared with those of a time true parallel cohort undergoing AA colonoscopy.

resultsIn 65 patients undergoing CCE, 36 (57%) were referred as an alternative to CT colonography. The completion rate in this group was 44% compared to 96% in CT colonography (p < 0.001). The PDR in complete CCE in this group was 75% in CCE compared to 20% in CT colonography (p < 0.001). The remaining 27 (43%) of the sample were referred for CCE as an alternative to AA colonoscopy. The completion rate in this group was 33% compared to 100% in AA colonoscopy (p < 0.001). The PDR in complete CCE in this group was 78% in CCE compared to 35% in AA colonoscopy (p = 0.013).

conclusionsThe completion rate of CCE following incomplete colonoscopy is inferior to that of CT colonography and AA colonoscopy. The PDR of CCE was high, indicating an acceptable sensitivity in complete investigations, but in our settings the completion rate of CCE on this indication is unacceptably low. CLINICAL

trial registrationNCT04307901 (ClinicalTrials.gov, March 13, 2020).

Indexed as

AnesthesiaCapsule EndoscopyColorectal NeoplasmsPolypsColonColonoscopyHumansProspective StudiesCCEColon capsule endoscopyColonoscopyCompletion rateCT colonographyIncomplete colonoscopy

Identifiers

PMID36471059
OpenAlexW4310786964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.