Evidence map›Paper›PMID 36470888›Full record

ArticleNPJ science of food2022

Wuliangye Baijiu but not ethanol reduces cardiovascular disease risks in a zebrafish thrombosis model.

Hui Zhu, Chaohua Lan, Dong Zhao, Ning Wang, Di Du, Huibo Luo, Huiqiang Lu, Zhifu Peng, Yumeng Wang, Zongwei Qiao and 2 more

Open access · goldAbstract read
In one paragraph

Article in NPJ science of food, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in nutrition · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Hypolipidemic and Antithrombotic Effect of 6'-Molecules (Basel, Switzerland) · 2024
    Article
  9. The combination of paeonol, diosmetin-7-Frontiers in pharmacology · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Hui Zhu *Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, 100048, Beijing, China.
Chaohua Lan *School of Bioengineering, Sichuan University of Science and Engineering, 643000, Zigong, China.
Dong ZhaoTechnology Research Center, Wuliangye Yibin Co., Ltd., 644007, Yibin, China. DongZhaoWLY@outlook.com.ORCID http://orcid.org/0000-0002-9033-9184
Ning WangSchool of Bioengineering, Sichuan University of Science and Engineering, 643000, Zigong, China.ORCID http://orcid.org/0000-0002-2236-6391
Di DuEnergy Sciences, ExxonMobil Technology and Engineering Company, Annandale, NJ, USA.
Huibo LuoSchool of Bioengineering, Sichuan University of Science and Engineering, 643000, Zigong, China. susehbluo@163.com.
Huiqiang LuCenter for Drug Screening and Research, School of Geography and Environmental Engineering, Gannan Normal University, 341000, Ganzhou, China.
Zhifu PengTechnology Research Center, Wuliangye Yibin Co., Ltd., 644007, Yibin, China.
Yumeng WangBristol Myers Squibb, Princeton, NJ, 08540, USA.
Zongwei QiaoTechnology Research Center, Wuliangye Yibin Co., Ltd., 644007, Yibin, China.
Yong HuangCenter for Drug Screening and Research, School of Geography and Environmental Engineering, Gannan Normal University, 341000, Ganzhou, China.
Baoguo SunBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, 100048, Beijing, China. sunbg@btbu.edu.cn.
Sichuan University of Science and Engineering · CNYibin University · CNBeijing Technology and Business University · CNGannan Normal University · CNBristol-Myers Squibb (United States) · USExxonMobil (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding how Baijiu facilitates blood circulation and prevents blood stasis is crucial for revealing the mechanism of Baijiu for cardiovascular disease (CVD) risk reduction. Here we established a zebrafish thrombosis model induced using arachidonic acid (AA) to quantitatively evaluate the antithrombotic effect of Wuliangye Baijiu. The prevention and reduction effects of aspirin, Wuliangye, and ethanol on thrombosis were compared using imaging and molecular characterization. Wuliangye Baijiu reduces thrombotic risks and oxidative stress in the AA-treated zebrafish, while ethanol with the same concentration has no similar effect. The prevention and reduction effects of Wuliangye on thrombosis are attributed to the change in the metabolic and signaling pathways related to platelet aggregation and adhesion, oxidative stress and inflammatory response.

Identifiers

PMID36470888
PMCPMC9723178
OpenAlexW4310779683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.