Evidence map›Paper›PMID 36470809›Full record

ArticleCurrent problems in pediatric and adolescent health care2022

Pulmonological issues.

Geovanny Perez, Lisa Young, Richard Kravitz, Daniel Sheehan, Laura Adang, Keith Van Haren, Jody L Lin, Nicole Nikki Jaffe, Dennis Kuo, Laura Ball and 4 more

Open access · greenAbstract read
In one paragraph

Article in Current problems in pediatric and adolescent health care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Guideline
  2. Rigorous genetic diagnosis review in natural history studies.Orphanet journal of rare diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Geovanny PerezStrong Memorial Hospital, Rochester, NY, USA. Electronic address: gperez@upa.chob.edu.
Lisa YoungChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Richard KravitzDuke Children's Hospital, Duke, NC, USA.
Daniel SheehanStrong Memorial Hospital, Rochester, NY, USA.
Laura AdangChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Keith Van HarenStanford University Medical Center, CA, USA.
Jody L LinUniversty of Utah, Salt Lake City, UT, USA.
Nicole Nikki JaffeChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Dennis KuoStrong Memorial Hospital, Rochester, NY, USA.
Laura BallChildren's National Medical Center, Washington DC, USA.
Jennifer KellerKennedy Krieger Institute, Baltimore, MD, USA.
Jeffrey SankDuke Children's Hospital, Duke, NC, USA.
Donna DiVitoChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Samira NaimeChildren's Mercy Hospital, Kansas City, MO, USA.
Children's Hospital of Philadelphia · USStrong Memorial Hospital · USDuke Children's Hospital & Health Center · USChildren's Mercy Hospital · USChildren's National · USKennedy Krieger Institute · USStanford University · US

Funding

Validation of the GMFC-MLDU54NS115052 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Laura Ann Adang, FLORIAN S EICHLER · 2019 to 2026
$14.3M
NINDS NIH HHS U54 NS115052
6 · The paper itself

Abstract

Pediatric leukodystrophies are rare neurodegenerative diseases involving multiple systems. Each form has unique neurologic features but are characterized by encephalopathy with accompanying impairments evidenced in reflexes, muscle tone and movement control. Weakness of expiratory, inspiratory, and upper airway muscles may lead to impaired airway secretion clearance resulting in recurrent respiratory infections, dysphagia, sleep-disordered breathing, restrictive lung disease, and ultimately chronic respiratory insufficiency.

Indexed as

Sleep Apnea SyndromesChildHumans

Identifiers

PMID36470809
PMCPMC11348663
OpenAlexW4311519971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.