Evidence map›Paper›PMID 36470783›Full record

ArticleTrends in parasitology2023

Macrophage to dendritic cell transitioning induced by Toxoplasma.

Jojo Reyes, George S Yap

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in parasitology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jojo ReyesCenter for Immunity and Inflammation, Department of Medicine, New Jersey Medical School, Rutgers University, Newark, NJ, USA.
George S YapCenter for Immunity and Inflammation, Department of Medicine, New Jersey Medical School, Rutgers University, Newark, NJ, USA. Electronic address: yapgs@njms.rutgers.edu.

Funding

Induction of effector lymphocyte lethargy by helminth coinfectionR01AI134040 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, YAP, GEORGE S. · 2017 to 2021
$2.9M
GDF-15 as a mediator of immune-regulated sickness response during infectionR21AI171670 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI YAP, GEORGE S. · 2023 to 2024
$417k
NIAID NIH HHS R01 AI134040NIAID NIH HHS R21 AI171670
6 · The paper itself

Abstract

Toxoplasma gondii exploits the migratory properties of monocytes and dendritic cells to promote tissue dissemination. Recently, ten Hoeve et al. reported that the parasite effector protein GRA28 conspires with host chromatin modifiers to confer dendritic cell-like features that convert sessile macrophages into migratory cells that transport infection to distal organs.

Indexed as

ToxoplasmaDendritic CellsMacrophagesdendritic cellmacrophageToxoplasma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.