Evidence map›Paper›PMID 36470479›Full record

ReviewNeuroscience2023

Activity-dependent Organization of Topographic Neural Circuits.

Hollis T Cline, Melissa Lau, Masaki Hiramoto

Abstract readReview
In one paragraph

Review in Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. ACS chemical neuroscience · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. AgRP neurons mediate activity-dependent development of oxytocin connectivity and autonomic regulation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hollis T ClineDepartment of Neuroscience and the Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA, USA. Electronic address: cline@scripps.edu.
Melissa LauDepartment of Neuroscience and the Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA, USA.
Masaki HiramotoDepartment of Neuroscience and the Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA, USA.

Funding

Activity-dependent Development of Visual System DevelopmentR01EY011261 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 1996 to 2018
$11.1M
Neurosciences Graduate Training ProgramT32NS061847 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Brenda L Bloodgood · 2008 to 2026
$7.7M
Experience-dependent Cellular Plasticity MechanismsR01EY031597 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2021 to 2025
$3.6M
Development of midbrain circuitryR01EY027437 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2018 to 2020
$1.9M
Transcriptome Analysis of Identified Cells in Developing Xenopus laevis CNSR01NS076006 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2011 to 2013
$1.4M
In vivo functional analysis of a neuronal membrane-specific proteasome complexR21NS114975 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2020 to 2020
$532k
NEI NIH HHS R01 EY011261NEI NIH HHS R01 EY027437NEI NIH HHS R01 EY031597NINDS NIH HHS R01 NS076006NINDS NIH HHS R21 NS114975NINDS NIH HHS T32 NS061847
6 · The paper itself

Abstract

Sensory information in the brain is organized into spatial representations, including retinotopic, somatotopic, and tonotopic maps, as well as ocular dominance columns. The spatial representation of sensory inputs is thought to be a fundamental organizational principle that is important for information processing. Topographic maps are plastic throughout an animal's life, reflecting changes in development and aging of brain circuitry, changes in the periphery and sensory input, and changes in circuitry, for instance in response to experience and learning. Here, we review mechanisms underlying the role of activity in the development, stability and plasticity of topographic maps, focusing on recent work suggesting that the spatial information in the visual field, and the resulting spatiotemporal patterns of activity, provide instructive cues that organize visual projections.

Indexed as

BrainBrain MappingAnimalsDominance, OcularLearningVisual Fieldsoptic flowspatiotemporal codingsynaptic plasticitytemporospatial codingtopographic mapVisual system

Identifiers

PMID36470479
PMCPMC9839526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.