Evidence map›Paper›PMID 36470463›Full record

ArticleThe Journal of pediatrics2023

Association of Childhood Blood Pressure with Left Atrial Size and Function: Study of High Blood Pressure in Pediatrics-Adult Hypertension in Youth (SHIP AHOY).

Edem Binka, Elaine M Urbina, Cedric Manlhiot, Tarek Alsaied, Tammy M Brady

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Left Atrial Strain in Pediatric Cardiology: Evidence to Date and Future Directions.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edem BinkaDivision of Pediatric Cardiology, Department of Pediatrics, University of Utah, Salt Lake City, UT. Electronic address: edem.binka@hsc.utah.edu.
Elaine M UrbinaDivision of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Cedric ManlhiotDivision of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
Tarek AlsaiedThe Heart Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.
Tammy M BradyDivision of Pediatric Nephrology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Training for Clinician Scientists in Pediatric Critical Cardiopulmonary DiseaseT32HL125239 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BEMBEA, MELANIA MARIA, EVERETT, ALLEN D · 2015 to 2024
$3.0M
Effect of dietary approaches on vascular function and blood pressure phenotype in youthR56HL139620 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BRADY, TAMMY MCLOUGHLIN · 2018 to 2018
$615k
NCATS NIH HHS UL1 TR001425NCATS NIH HHS UL1 TR002319NHLBI NIH HHS R56 HL139620NHLBI NIH HHS T32 HL125239
6 · The paper itself

Abstract

OBJECTIVE(S): To evaluate the cross-sectional association of cardiovascular disease risk factors with left atrial (LA) size and function among healthy youth, aged 11-18 years, with a wide range of blood pressures (BPs). STUDY

designEchocardiographic images of youth enrolled in the Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth study were analyzed for LA measurements. The association of casual BP, ambulatory BP, and other cardiovascular disease risk factors with LA size and function were determined using descriptive statistics and multivariable regression. Regression models adjusting for age, sex, race, and body mass index z score determined the independent association between ambulatory systolic BP indices (mean systolic BP/50th %ile systolic BP) and BP phenotypes with LA outcomes while exploratory analyses investigated for additional predictors of LA outcomes.

resultsThe study population consisted of 347 youth: median age 15.7 years, 60% male and 40% non-White. Greater-risk casual systolic BP groups had worse cardiometabolic profiles but no differences in LA size and function. Each 0.1 increase in ambulatory systolic BP day or night index was associated with a 9.9 mL/m

conclusionsIncreasing ambulatory systolic BP and ambulatory hypertension are independently associated with LAV/BSA.

Indexed as

Atrial FibrillationHypertensionAdolescentBlood PressureBlood Pressure Monitoring, AmbulatoryChildCross-Sectional StudiesFemaleHeart AtriaHumansMalecardiovascular risk factorsechocardiographyhypertensionleft atrial enlargementleft atrial straintarget organ injury

Identifiers

PMID36470463
PMCPMC10121756

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.