Evidence map›Paper›PMID 36469813›Full record

ArticleAdvanced healthcare materials2023

Amyloid-Based Albumin Hydrogels.

Carolina Diaz, Dimitris Missirlis

Open access · hybridAbstract read
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. ACS applied polymer materials · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Amyloid-Based Albumin Hydrogels.Advanced healthcare materials · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Carolina DiazDepartment of Cellular Biophysics, Max-Planck-Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.ORCID 0000-0003-0858-0989
Dimitris MissirlisDepartment of Cellular Biophysics, Max-Planck-Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.ORCID 0000-0003-1874-676X
Consejo Nacional de Investigaciones Científicas y Técnicas · ARMax Planck Institute for Medical Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid fibrils may serve as building blocks for the preparation of novel hydrogel materials from abundant, low-cost, and biocompatible polypeptides. This work presents the formation of physically cross-linked, self-healing hydrogels based on bovine serum albumin at room temperature through a straightforward disulfide reduction step induced by tris (2-carboxyethyl) phosphine hydrochloride. The structure and surface charge of the amyloid-like fibrils is determined by the pH of the solution during self-assembly, giving rise to hydrogels with distinct physicochemical properties. The hydrogel surface can be readily functionalized with the extracellular matrix protein fibronectin and supports cell adhesion, spreading, and long-term culture. This study offers a simple, versatile, and inexpensive method to prepare amyloid-based albumin hydrogels with potential applications in the biomedical field.

Indexed as

AmyloidHydrogelsExtracellular Matrix ProteinsSerum Albumin, BovineAmyloidExtracellular Matrix ProteinsHydrogelsSerum Albumin, Bovineantifoulingcell mechanosensingfibrillar hydrogelsself-assemblysustainable materials

Identifiers

PMID36469813
PMCPMC11469233
OpenAlexW4310775483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.