Evidence map›Paper›PMID 36469781›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

FtsEX-independent control of RipA-mediated cell separation in

Quentin Gaday, Daniela Megrian, Giacomo Carloni, Mariano Martinez, Bohdana Sokolova, Mathilde Ben Assaya, Pierre Legrand, Sebastien Brûlé, Ahmed Haouz, Anne Marie Wehenkel and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. An activator of a two-component system controls cell separation and intrinsic drug resistance inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. The Exoproteome and Surfaceome of ToxigenicJournal of proteome research · 2025
    Article
  10. Outer membrane barrier impairment byMicrobiology (Reading, England) · 2024
    Article
  11. Article
  12. Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Quentin GadayUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0002-0455-4786
Daniela MegrianUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0002-6272-6814
Giacomo CarloniUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0003-1984-8231
Mariano MartinezUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0003-4460-8045
Bohdana SokolovaUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0003-3751-7129
Mathilde Ben AssayaUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.
Pierre LegrandSynchrotron SOLEIL, 91192 Gif-sur-Yvette, France.ORCID 0000-0003-2431-2255
Sebastien BrûléPlate-forme de biophysique moléculaire, Centre de Ressources et de Recherches Technologiques, Institut Pasteur, CNRS, F-75015 Paris, France.
Ahmed HaouzPlate-forme de cristallographie, Centre de Ressources et de Recherches Technologiques, Institut Pasteur, CNRS, F-75015, Paris, France.ORCID 0000-0003-1196-1635
Anne Marie WehenkelUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0003-2327-6512
Pedro M AlzariUnité de Microbiologie Structurale, Institut Pasteur, CNRS, Université Paris Cité, Paris 75015, France.ORCID 0000-0002-4233-1903
Centre National de la Recherche Scientifique · FRSynchrotron soleil · FR

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

The bacterial cell wall is a multi-layered mesh, whose major component is peptidoglycan (PG), a sugar polymer cross-linked by short peptide stems. During cell division, a careful balance of PG synthesis and degradation, precisely coordinated both in time and space, is necessary to prevent uncontrolled destruction of the cell wall. In

Indexed as

ActinomycetalesBacterial ProteinsCell WallN-Acetylmuramoyl-L-alanine AmidasePeptidoglycanPhylogenyBacterial ProteinsN-Acetylmuramoyl-L-alanine AmidasePeptidoglycanbacterial cell divisionCorynebacterium glutamicumpeptidoglycanstructural biology

Identifiers

PMID36469781
PMCPMC9897464
OpenAlexW4311499951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.