Evidence map›Paper›PMID 36469778›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration.

Soumitra Mitra, Sulochana Devi, Mi-Sun Lee, Jonathan Jui, Aresh Sahu, Daniel Goldman

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  8. The neuroimmune interface in retinal regeneration.Progress in retinal and eye research · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Soumitra MitraMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.
Sulochana DeviMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.
Mi-Sun LeeMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.
Jonathan JuiMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-1357-608X
Aresh SahuMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-8673-9807
Daniel GoldmanMichigan Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-0013-1188
University of Michigan · US

Funding

Mechanisms underlying Muller glia’s regenerative potentialR01EY032867 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDMAN, DANIEL J · 2021 to 2025
$1.9M
NEI NIH HHS R01 EY032867
6 · The paper itself

Abstract

In the zebrafish retina, Müller glia (MG) can regenerate retinal neurons lost to injury or disease. Even though zebrafish MG share structure and function with those of mammals, only in zebrafish do MG function as retinal stem cells. Previous studies suggest dying neurons, microglia/macrophage, and T cells contribute to MG's regenerative response [White et al.,

Indexed as

ZebrafishZebrafish ProteinsAnimalsAnimals, Genetically ModifiedCell ProliferationEndothelial CellsEpendymoglial CellsMammalsNerve RegenerationNeurogliaRegenerationRetinaSignal TransductionZebrafish ProteinsneurodegenerationNotchPgfreprogrammingstem cell

Identifiers

PMID36469778
PMCPMC9897474
OpenAlexW4310938418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.