Evidence map›Paper›PMID 36469682›Full record

ArticleJournal of applied gerontology : the official journal of the Southern Gerontological Society2023

Association of Race and Income with Incident Diagnosis of Alzheimer's Disease and Related Dementias among Black and White Older Adults.

Laura M Keohane, Sayeh Nikpay, Kyle Braun, Audrey Cheng, David Stevenson, Melinda B Buntin, Danxia Yu, William J Blot, Loren Lipworth

Open access · greenAbstract read
In one paragraph

Article in Journal of applied gerontology : the official journal of the Southern Gerontological Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Social determinants of dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Laura M KeohaneDepartment of Health Policy, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-9400-0575
Sayeh Nikpay43353University of Minnesota School of Public Health, MN, USA.
Kyle BraunDepartment of Health Policy, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
Audrey ChengDepartment of Health Policy, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
David StevensonDepartment of Health Policy, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
Melinda B BuntinDepartment of Health Policy, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
Danxia YuDepartment of Medicine, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
William J BlotDepartment of Medicine, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
Loren LipworthDepartment of Medicine, 12327Vanderbilt University School of Medicine, Nashville, TN, USA.
Vanderbilt University · USUniversity of Minnesota · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Southern Community Cohort StudyU01CA202979 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., SHRUBSOLE, MARTHA J. · 2016 to 2025
$22.0M
NCI NIH HHS P30 CA068485NCI NIH HHS U01 CA202979
6 · The paper itself

Abstract

To investigate how differences in income and education levels may contribute to disparities in incidence of Alzheimer's disease and related dementia (ADRD), we compared ADRD incidence in traditional Medicare claims for 11,132 Black and 7703 White participants aged 65 and over from a predominantly low-income cohort. We examined whether the relationship between ADRD incidence and race varied by income or education. Based on 2015 incident ADRD diagnoses, Black and White participants had unadjusted incidence rates of 26.5 and 23.2 cases per 1000 person-years, respectively (rate ratio 1.14, 95% CI 1.05-1.25). In multivariable Cox proportional hazard models, the relationship between race and incident ADRD diagnosis did not vary by education level (p-interaction = 0.748) but was modified by income level (p-interaction = 0.007), with higher ADRD incidence among Black participants observed only among higher income groups. These results highlight the importance of understanding how race and economic factors influence ADRD incidence and diagnosis rates.

Indexed as

Alzheimer DiseaseAgedHumansIncomeMedicarePovertyUnited StatesWhiteAlzheimer’s diseasedementiaincidenceincomerace

Identifiers

PMID36469682
PMCPMC10081951
OpenAlexW4311623924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.