Evidence map›Paper›PMID 36469091›Full record

ArticleAge and ageing2022

Prevalence and outcomes of atrial fibrillation in older people living in care homes in Wales: a routine data linkage study 2003-2018.

Leona A Ritchie, Stephanie L Harrison, Peter E Penson, Ashley Akbari, Fatemeh Torabi, Joe Hollinghurst, Daniel Harris, Oluwakayode B Oke, Asangaedem Akpan, Julian P Halcox and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Leona A RitchieLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0002-0392-1767
Stephanie L HarrisonLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0002-8846-0946
Peter E PensonLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0001-6763-1489
Ashley AkbariPopulation Data Science, Health Data Research UK, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Fatemeh TorabiPopulation Data Science, Administrative Data Research Wales, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Joe HollinghurstPopulation Data Science, Administrative Data Research Wales, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.ORCID 0000-0002-3556-2017
Daniel HarrisPopulation Data Science, Administrative Data Research Wales, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Oluwakayode B OkeLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.
Asangaedem AkpanMusculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Julian P HalcoxPopulation Data Science, Administrative Data Research Wales, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Sarah E RodgersDepartment of Public Health, Policy and Systems, Institute of Population Health, University of Liverpool, Liverpool L69 3GF, UK.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.
Deirdre A LaneLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK.
University of Liverpool · GBSwansea University · GB

Funding

British Heart FoundationChief Scientist OfficeDepartment of HealthMedical Research CouncilWellcome Trust
6 · The paper itself

Abstract

objectiveTo determine atrial fibrillation (AF) prevalence and temporal trends, and examine associations between AF and risk of adverse health outcomes in older care home residents.

methodsRetrospective cohort study using anonymised linked data from the Secure Anonymised Information Linkage Databank on CARE home residents in Wales with AF (SAIL CARE-AF) between 2003 and 2018. Fine-Gray competing risk models were used to estimate the risk of health outcomes with mortality as a competing risk. Cox regression analyses were used to estimate the risk of mortality.

resultsThere were 86,602 older care home residents (median age 86.0 years [interquartile range 80.8-90.6]) who entered a care home between 2003 and 2018. When the pre-care home entry data extraction was standardised, the overall prevalence of AF was 17.4% (95% confidence interval 17.1-17.8) between 2010 and 2018. There was no significant change in the age- and sex-standardised prevalence of AF from 16.8% (15.9-17.9) in 2010 to 17.0% (16.1-18.0) in 2018. Residents with AF had a significantly higher risk of cardiovascular mortality (adjusted hazard ratio [HR] 1.27 [1.17-1.37], P < 0.001), all-cause mortality (adjusted HR 1.14 [1.11-1.17], P < 0.001), ischaemic stroke (adjusted sub-distribution HR 1.55 [1.36-1.76], P < 0.001) and cardiovascular hospitalisation (adjusted sub-distribution HR 1.28 [1.22-1.34], P < 0.001).

conclusionsOlder care home residents with AF have an increased risk of adverse health outcomes, even when higher mortality rates and other confounders are accounted for. This re-iterates the need for appropriate oral anticoagulant prescription and optimal management of cardiovascular co-morbidities, irrespective of frailty status and predicted life expectancy.

Indexed as

Atrial FibrillationBrain IschemiaStrokeAgedAged, 80 and overAnticoagulantsHumansInformation Storage and RetrievalPrevalenceRetrospective StudiesRisk FactorsWalesAnticoagulantsAtrial fibrillationcare homeshealth outcomesolder peopleprevalencestroke

Identifiers

PMID36469091
PMCPMC9721338
OpenAlexW4310714213

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.