Evidence map›Paper›PMID 36469004›Full record

ArticleMolecular cancer research : MCR2023

ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks.

Thomas E Bass, Donald E Fleenor, Paige E Burrell, Michael B Kastan

Open access · greenAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. ATM interaction with GRP94 modulates oncogenic receptor expression and signaling and microglial activation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. A dual role of Cohesin in DNA DSB repair.Nature communications · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thomas E BassDepartment of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina.ORCID 0000-0002-8618-5266
Donald E FleenorDepartment of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina.ORCID 0000-0002-7534-7637
Paige E BurrellDepartment of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina.ORCID 0000-0002-7142-8974
Michael B KastanDepartment of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina.ORCID 0000-0002-1719-7562
Duke University · US

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
The role of ATM in Metabolic Stress ResponsesR01CA157216 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KASTAN, MICHAEL B · 2011 to 2020
$3.1M
NCI NIH HHS P30 CA014236NCI NIH HHS R01 CA157216
6 · The paper itself

Abstract

implicationsMultiple members of the cohesin complex are involved in the regulation of DNA replication and transcription in the vicinity of DNA double-strand breaks and their role(s) are regulated by the ATM kinase.

Indexed as

Cell Cycle ProteinsDNA ReplicationAtaxia Telangiectasia Mutated ProteinsCohesinsDNAHumansPhosphorylationAtaxia Telangiectasia Mutated ProteinsATM protein, humanCell Cycle ProteinsCohesinsDNA

Identifiers

PMID36469004
PMCPMC9992094
OpenAlexW4310701345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.