Evidence map›Paper›PMID 36469003›Full record

ArticleThe Journal of physiology2023

Subcellular diversity of Nav1.5 in cardiomyocytes: distinct functions, mechanisms and targets.

Gerard A Marchal, Carol Ann Remme

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Sodium Channel mRNA Binding Proteins.JACC. Basic to translational science · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. SCN5A variant type-dependent risk prediction in Brugada syndrome.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. SCN5A-1795insD founder variant: a unique Dutch experience spanning 7 decades.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Review
  16. Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Gerard A MarchalDepartment of Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Heart Failure & Arrhythmias, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-7353-0235
Carol Ann RemmeDepartment of Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Heart Failure & Arrhythmias, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-0095-0084
Amsterdam Neuroscience · NLInstituto de Óptica "Daza de Valdés" · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cardiomyocytes, the rapid depolarisation of the membrane potential is mediated by the α-subunit of the cardiac voltage-gated Na

Indexed as

Arrhythmias, CardiacMyocytes, CardiacAction PotentialsDeath, Sudden, CardiacHumansMembrane PotentialsNAV1.5 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium Channelarrhythmiacardiomyocyteelectrophysiologymicrodomainvoltage-gated sodium channel

Identifiers

PMID36469003
OpenAlexW4310701755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.