Evidence map›Paper›PMID 36468882›Full record

ArticlemBio2022

Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.

Bradley Benjamin, Yehuda Goldgur, Nikolaus Jork, Henning J Jessen, Beate Schwer, Stewart Shuman

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Bradley BenjaminMolecular Biology Program, Memorial Sloan Kettering Cancer Centergrid.51462.34, New York, New York, USA.
Yehuda GoldgurStructural Biology Program, Memorial Sloan Kettering Cancer Centergrid.51462.34, New York, New York, USA.
Nikolaus JorkInstitute of Organic Chemistry, University of Freiburggrid.5963.9, Freiburg, Germany.
Henning J JessenInstitute of Organic Chemistry, University of Freiburggrid.5963.9, Freiburg, Germany.
Beate SchwerDepartment of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, USA.
Stewart ShumanMolecular Biology Program, Memorial Sloan Kettering Cancer Centergrid.51462.34, New York, New York, USA.
Memorial Sloan Kettering Cancer Center · USUniversity of Freiburg · DECornell University · USKettering University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Mechanisms of DNA and RNA TransactionsR35GM126945 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Stewart H Shuman · 2018 to 2026
$8.9M
Inositol pyrophosphate dynamics affect RNA 3'-processing/transcription terminationR01GM134021 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BEATE SCHWER · 2019 to 2026
$2.8M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM134021NIGMS NIH HHS R35 GM126945
6 · The paper itself

Abstract

Expression of the fission yeast Schizosaccharomyces pombe phosphate regulon is sensitive to the intracellular level of the inositol pyrophosphate signaling molecule 1,5-IP

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsAdenosine DiphosphateAdenosine TriphosphateDiphosphatesHumansInositol PhosphatesMultifunctional EnzymesPhosphotransferases (Phosphate Group Acceptor)PyrophosphatasesAdenosine DiphosphateAdenosine TriphosphateAsp1 protein, S pombeDiphosphatesdiphosphoric acidInositol PhosphatesMultifunctional EnzymesPhosphotransferases (Phosphate Group Acceptor)PPIP5K2 protein, humanPyrophosphatasesSchizosaccharomyces pombe ProteinsAsp1 kinaseinositol pyrophosphatesNTP donor specificitySchizosaccharomyces pombesubstrate binding

Identifiers

PMID36468882
PMCPMC9765450
OpenAlexW4310701665

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.