Evidence map›Paper›PMID 36468617›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2023

Self-Powered Programming of Fibroblasts into Neurons via a Scalable Magnetoelastic Generator Array.

Alberto Libanori, Jennifer Soto, Jing Xu, Yang Song, Jana Zarubova, Trinny Tat, Xiao Xiao, Shou Zheng Yue, Steven J Jonas, Song Li and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 43 citations in OpenAlex.

  1. Advances in Wearable Bioimaging.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  2. Article
  3. Artificial Intelligence-Driven Soft Bioelectronics for Self-Powered Respiration Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Advances in Soft Mechanocaloric Materials.Advanced functional materials · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Implantable Self-Powered Systems for Electrical Stimulation Medical Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alberto LibanoriDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.ORCID https://orcid.org/0000-0003-1913-3017
Jennifer SotoDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Jing XuDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Yang SongDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Jana ZarubovaDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Trinny TatDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Xiao XiaoDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.ORCID https://orcid.org/0000-0002-7861-5596
Shou Zheng YueCalifornia NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Steven J JonasCalifornia NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Song LiDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Jun ChenDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.ORCID https://orcid.org/0000-0002-3439-0495
University of California, Los Angeles · USCalifornia NanoSystems Institute · USChildren's Hospital of Los Angeles · US

Funding

Multimodal wireless electrical stimulation for tissue regenerationR01NS126918 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Song Li, John Rogers · 2022 to 2026
$2.4M
Nanoscience-Inspired Acoustofluidic Assembly Lines for Gene and Cellular TherapiesDP5OD028181 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JONAS, STEVEN JOHN · 2019 to 2023
$1.9M
Regulation of cell reprogramming by matrix stiffnessR01GM143485 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, SONG · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM143485NIH HHS DP5 OD028181NIH HHS GM143485NIH HHS NS126918NINDS NIH HHS R01 NS126918
6 · The paper itself

Abstract

Developing scalable electrical stimulating platforms for cell and tissue engineering applications is limited by external power source dependency, wetting resistance, microscale size requirements, and suitable flexibility. Here, a versatile and scalable platform is developed to enable tunable electrical stimulation for biological applications by harnessing the giant magnetoelastic effect in soft systems, converting gentle air pressure (100-400 kPa) to yield a current of up to 10.5 mA and a voltage of 9.5 mV. The platform can be easily manufactured and scaled up for integration in multiwell magnetoelastic plates via 3D printing. The authors demonstrate that the electrical stimulation generated by this platform enhances the conversion of fibroblasts into neurons up to 2-fold (104%) and subsequent neuronal maturation up to 3-fold (251%). This easily configurable electrical stimulation device has broad applications in high throughput organ-on-a-chip systems, and paves the way for future development of neural engineering, including cellular therapy via implantable self-powered electrical stimulation devices.

Indexed as

Electric Power SuppliesNeuronsFibroblastsProstheses and ImplantsTissue Engineeringcell reprogrammingelectric stimulationmagnetoelastic effectmagnetoelastic generatorsneural engineering

Identifiers

PMID36468617
PMCPMC10462379
OpenAlexW4310701488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.