Evidence map›Paper›PMID 36468556›Full record

ArticleActa crystallographica. Section C, Structural chemistry2022

N-Cycloamino substituent effects on the packing architecture of ortho-sulfanilamide molecular crystals and their in silico carbonic anhydrase II and IX inhibitory activities.

Sherif O Kolade, Josephat U Izunobi, Allen T Gordon, Eric C Hosten, Idris A Olasupo, Adeniyi S Ogunlaja, Olayinka T Asekun, Oluwole B Familoni

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sherif O KoladeDepartment of Chemistry, University of Lagos, Akoka-Yaba, Lagos, Nigeria.ORCID 0000-0002-0940-3928
Josephat U IzunobiDepartment of Chemistry, University of Lagos, Akoka-Yaba, Lagos, Nigeria.ORCID 0000-0002-6315-4969
Allen T GordonDepartment of Chemistry, Nelson Mandela University, Port Elizabeth, 6031, South Africa.
Eric C HostenDepartment of Chemistry, Nelson Mandela University, Port Elizabeth, 6031, South Africa.
Idris A OlasupoDepartment of Chemistry, University of Lagos, Akoka-Yaba, Lagos, Nigeria.
Adeniyi S OgunlajaDepartment of Chemistry, Nelson Mandela University, Port Elizabeth, 6031, South Africa.
Olayinka T AsekunDepartment of Chemistry, University of Lagos, Akoka-Yaba, Lagos, Nigeria.ORCID 0000-0002-3875-003X
Oluwole B FamiloniDepartment of Chemistry, University of Lagos, Akoka-Yaba, Lagos, Nigeria.ORCID 0000-0002-5480-232X
University of Lagos · NGNelson Mandela University · ZA

Funding

National Research Foundation (NRF) of South Africa Grant No: 129887Nigerian Government TetFund IBR CRC/TETFUND/No. 2018/016University of Lagos Central Research Committee CRC No. 2015/25
6 · The paper itself

Abstract

In the search for new `sulfa drugs' with therapeutic properties, o-nitrosulfonamides and N-cycloamino-o-sulfanilamides were synthesized and characterized using techniques including

Indexed as

Aniline CompoundsCarbonic Anhydrase IICrystallography, X-RayHumansHydrogen BondingMolecular Docking SimulationPiperidinesPyrrolidinesSpectroscopy, Fourier Transform InfraredSulfanilamideAniline CompoundsCarbonic Anhydrase IIPiperidinesPyrrolidinesSulfanilamidecrystal structurecycloaminoDFTinhibitory activitynitrosulfonamidepacking architectureSC-XRDsulfanilamide

Identifiers

PMID36468556
PMCPMC9720883
OpenAlexW4308732929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.