Evidence map›Paper›PMID 36468191›Full record

ArticleAddiction (Abingdon, England)2023

Safety in solitude? Competing risks and drivers of solitary drug use among women who inject drugs and implications for overdose detection.

Joseph G Rosen, Jennifer L Glick, Leanne Zhang, Lyra Cooper, Praise F Olatunde, Danielle Pelaez, Saba Rouhani, Kimberly L Sue, Ju Nyeong Park

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. The Drug Market's Impact on the Overdose Risk Environment for Women Who Use Drugs During the COVID-19 Pandemic.Journal of urban health : bulletin of the New York Academy of Medicine · 2026
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  14. Predictors of overdose response hotline use for mental health and fatal overdose prevention.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Using illicit drugs alone in Vancouver, Canada: a gender-based analysis.Substance abuse treatment, prevention, and policy · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Joseph G RosenDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-4991-4033
Jennifer L GlickDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Leanne ZhangDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-3255-9269
Lyra CooperDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Praise F OlatundeDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Danielle PelaezDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Saba RouhaniDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Kimberly L SueNational Harm Reduction Coalition, New York, New York, USA.
Ju Nyeong ParkDepartment of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI Brandon David Lewis Marshall · 2018 to 2026
$23.4M
Viral Load Trajectories and Dynamics among People Living with HIV in Rakai, Uganda: A Mixed-Methods StudyF31MH126796 · NIMH · JOHNS HOPKINS UNIVERSITY · PI ROSEN, JOSEPH GREGORY · 2021 to 2022
$79k
NIAID NIH HHS P30 AI094189NIGMS NIH HHS P20 GM125507NIMH NIH HHS F31 MH126796
6 · The paper itself

Abstract

BACKGROUND AND

aimsSolitary drug use (SDU) can amplify risks of fatal overdose. We examined competing risks and drivers of SDU, as well as harm reduction strategies implemented during SDU episodes, among women who inject drugs (WWID).

designA cross-sectional qualitative study, including telephone and face-to-face in-depth interviews.

settingBaltimore City, MD, USA.

participantsTwenty-seven WWID (mean age = 39 years, 67% white, 74% injected drugs daily) recruited via outreach and street intercept (April-September 2021). MEASUREMENTS: Interviews explored the physical (i.e. indoor/private, outdoor/public) and social (i.e. alone, accompanied) risk environments in which drug use occurred. Guided by the principles of emergent design, we used thematic analysis to interrogate textual data, illuminating women's preferences/motivations for SDU and strategies for minimizing overdose risks when using alone.

findingsMany participants reported experiences with SDU, despite expressed preferences for accompanied drug use. SDU motivations clustered around three primary drivers: (1) avoiding opioid withdrawal, (2) preferences for privacy when using drugs and (3) safety concerns, including threats of violence. Participants nevertheless acknowledged the dangers of SDU and, at times, took steps to mitigate overdose risk, including naloxone possession, communicating to peers when using alone ('spotting') and using drugs in public spaces.

conclusionsWWID appear to engage frequently in SDU due to constraints of the physical and social environments in which they use drugs. They express a preference for accompanied drug use in most cases and report implementing strategies to mitigate their overdose risk, especially when using drugs alone.

Indexed as

Drug OverdoseOpioid-Related DisordersSubstance Abuse, IntravenousAdultCross-Sectional StudiesFemaleHarm ReductionHumansNaloxoneNaloxoneDrug overdoseinjection drug useopioidsqualitative researchsolitary drug usesubstance useusing drugs alone

Identifiers

PMID36468191
PMCPMC10073256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.