SynthesisFrontiers in neurology2022
Epidemiology of neurodegenerative diseases in the East African region: A meta-analysis.
Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Melatonin as a protector against endocrine disruption across tissues: A systematic review.Physiological reports · 2026Pooled it
- Suicide in neurodegenerative diseases: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Physiological significance of autocrine orexinergic signaling in extra-hypothalamic tissues.Physiological reports · 2026Pooled it
- Genetic aetiology of global developmental delay and intellectual disability in Africa: a scoping review.Frontiers in genetics · 2026Pooled it
- Epidemiological distribution of bacterial meningitis infections in South Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- A scoping review of the prevalence of antimicrobial-resistant pathogens and signatures in ready-to-eat street foods in Africa: implications for public health.Frontiers in microbiology · 2025Pooled it
- Prevalence and epidemiological distribution of substance use among people living with HIV in the East African region: a meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Multinational appraisal of the epidemiological distribution of opioid fatalities: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Pooled it
- Gut microbiota and brain aging: a comparative review of African and western populations.Frontiers in aging neuroscience · 2026Review
- Fruits as a preventative strategy: exploring their role in neurodegenerative disease management.Neurodegenerative disease management · 2025Review
- Exploring the Neuroprotective Potentials of Flavonoid Metabolites inJournal of experimental pharmacology · 2025Review
- The burden of unlawful use of opioid and associated epidemiological characteristics in Africa: A scoping review.PloS one · 2025Article
- Exosome engineering for targeted therapy of brain-infecting pathogens: molecular tools, delivery platforms, and translational advances.Frontiers in medical technology · 2025Review
- Unraveling the mechanistic interplay of mediators orchestrating the neuroprotective potential of harmine.Pharmacological reports : PR · 2024Review
- Spectrum of neurodegenerative disorders in neurology outpatient department: A cross-sectional study.Health science reports · 2024Article
- New Insights into Oxidative Stress and Inflammatory Response in Neurodegenerative Diseases.International journal of molecular sciences · 2024Review
- Challenges in evaluating cognitive impairment in diabetics in the Democratic Republic of the Congo.Dementia & neuropsychologia · 2024Article
- Biological activities of astaxanthin in the treatment of neurodegenerative diseases.Neurodegenerative disease management · 2024Review
- UCP-LF and other assay methods for schistosome circulating anodic antigen between 1978 and 2022.Biology methods & protocols · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: There is a scarcity of epidemiological data on neurodegenerative diseases (NDs) in East Africa. This meta-analysis provides the regional prevalence of NDs, their contributing factors, and evidence of change over time concerning gender per age or year. Methods: Articles were retrieved from electronic databases following the PRISMA standard. Results: Forty-two studies were reviewed, and 25 were meta-analyzed with a random-effects model. The pool estimate proportion of 15.27%, 95% CI (0.09-0.23) (I Conclusion: There is a high prevalence of NDs in the East African region, which could impact life expectancy, morbidity, and quality of life. Thus, early screening and regular surveillance could assist in management strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.